@article{larochelle_intolerance_2025,

title = {Intolerance of Uncertainty and Emotion Dysregulation as Predictors of Generalized Anxiety Disorder Severity in a Clinical Population},

author = {S. Larochelle and M. J. Dugas and F. Langlois and P. Gosselin and G. Belleville and S. Bouchard},

url = {https://www.scopus.com/inward/record.uri?eid=2-s2.0-86000587548&doi=10.3390%2fjcm14051502&partnerID=40&md5=ea6c43194a821d0a0623385714231936},

doi = {10.3390/jcm14051502},

issn = {20770383 (ISSN)},

year  = {2025},

date = {2025-01-01},

journal = {Journal of Clinical Medicine},

volume = {14},

number = {5},

abstract = {Background/objectives: Several factors have been shown to play a role in the development and maintenance of generalized anxiety disorder (GAD), including intolerance of uncertainty and emotion dysregulation. Although the individual contribution of both of these factors is well documented, their combined effect has yet to be studied in a clinical population with GAD. The aim of the present study was to examine the relative contribution of intolerance of uncertainty and emotion dysregulation to the prediction of worry and GAD severity in adults with GAD. Methods: The sample consisted of 108 participants diagnosed with GAD. The participants completed measures of worry, GAD severity, depressive symptoms, intolerance of uncertainty, and emotion dysregulation. Results: Multiple regression indicated that both intolerance of uncertainty and emotion dysregulation significantly contributed to both worry and GAD severity, over and above the contribution of depressive symptoms. Of note, the model explained 36% of the variance in GAD severity scores. Conclusions: The present results provide preliminary evidence of complementarity among dominant models of GAD, and point to the potential role of integrative conceptualizations and treatment strategies for GAD. © 2025 by the authors.},

note = {Publisher: Multidisciplinary Digital Publishing Institute (MDPI)},

keywords = {adult, aged, article, Beck Depression Inventory, clinical population, comorbidity, controlled study, Depression, difficulties in emotion regulation scale, disease severity, emotion, emotion dysregulation, emotion regulation, employment status, female, generalized anxiety disorder, human, intolerance of uncertainty, Intolerance of Uncertainty Scale, major clinical study, male, patient worry, penn state worry questionnaire, prediction, predictive model, psychotherapy, Severity of Illness Index, sociodemographics, theoretical model},

pubstate = {published},

tppubtype = {article}

}