Slide
Centre Interdisciplinaire
de Recherche et d’Innovation
en Cybersécurité et Société
de Recherche et d’Innovation
en Cybersécurité et Société
1.
Elhajjout, A.; Houda, Z. A. E.; Moudoud, H.; Brik, B.; Jan, M. A.
Federated Large Language Models for A Trustworthy and Privacy-Preserving Healthcare: Applications, Challenges, and Future Research Directions Journal Article
In: IEEE Journal of Biomedical and Health Informatics, 2026, ISSN: 21682194 (ISSN).
Abstract | Links | BibTeX | Tags: Application research, Artificial intelligence, digital health, Distributed computer systems, Federated learning, Fine tuning, Health care, Health care application, Healthcare AI, human, Internet, Internet of medical thing, Internet of Medical Things, Language model, Large language model, large language models, Learning systems, male, Medical computing, natural language processing, Parameter-efficient fine-tuning, patient coding, Privacy, Privacy preservation, Privacy preserving, Privacy-preserving techniques, review, Sensitive data, trustworthiness
@article{elhajjoutFederatedLargeLanguage2026,
title = {Federated Large Language Models for A Trustworthy and Privacy-Preserving Healthcare: Applications, Challenges, and Future Research Directions},
author = {A. Elhajjout and Z. A. E. Houda and H. Moudoud and B. Brik and M. A. Jan},
url = {https://www.scopus.com/pages/publications/105034640126?origin=resultslist},
doi = {10.1109/JBHI.2026.3679612},
issn = {21682194 (ISSN)},
year = {2026},
date = {2026-01-01},
journal = {IEEE Journal of Biomedical and Health Informatics},
publisher = {Institute of Electrical and Electronics Engineers Inc.},
abstract = {Large-scale foundation models, especially Federated Large Language Models (FLLMs), aim to transform digital health by enabling clinically-grade natural language processing while keeping sensitive data local. However, their adoption is hindered by two main issues: (i) the computational and communication burden of parameter-rich models on resource-constrained Internet-of-Medical-Things (IoMT) devices, and (ii) performance degradation caused by Non-Independent and Identically Distributed (Non-IID) patient data. This paper presents a comprehensive survey of Federated Learning (FL) for LLMs in Healthcare (FedMed-LLMs). We review the foundations of FL and medical LLMs. Then, we present the FL-enabled LLMs applications in healthcare, and we examine their issues in terms of privacy, robustness, and trustworthiness. Finally, we present a set of core research problems and a comprehensive research agenda that identifies future directions for building robust and scalable FedMed-LLMs systems. © 2013 IEEE.},
keywords = {Application research, Artificial intelligence, digital health, Distributed computer systems, Federated learning, Fine tuning, Health care, Health care application, Healthcare AI, human, Internet, Internet of medical thing, Internet of Medical Things, Language model, Large language model, large language models, Learning systems, male, Medical computing, natural language processing, Parameter-efficient fine-tuning, patient coding, Privacy, Privacy preservation, Privacy preserving, Privacy-preserving techniques, review, Sensitive data, trustworthiness},
pubstate = {published},
tppubtype = {article}
}
Large-scale foundation models, especially Federated Large Language Models (FLLMs), aim to transform digital health by enabling clinically-grade natural language processing while keeping sensitive data local. However, their adoption is hindered by two main issues: (i) the computational and communication burden of parameter-rich models on resource-constrained Internet-of-Medical-Things (IoMT) devices, and (ii) performance degradation caused by Non-Independent and Identically Distributed (Non-IID) patient data. This paper presents a comprehensive survey of Federated Learning (FL) for LLMs in Healthcare (FedMed-LLMs). We review the foundations of FL and medical LLMs. Then, we present the FL-enabled LLMs applications in healthcare, and we examine their issues in terms of privacy, robustness, and trustworthiness. Finally, we present a set of core research problems and a comprehensive research agenda that identifies future directions for building robust and scalable FedMed-LLMs systems. © 2013 IEEE.
2.
Fareedi, A. A.; Gagnon, S.; Ghazawneh, A.; Valverde, R.
Semantic Fusion of Health Data: Implementing a Federated Virtualized Knowledge Graph Framework Leveraging Ontop System Journal Article
In: Future Internet, vol. 17, no. 6, 2025, ISSN: 19995903 (ISSN), (Publisher: Multidisciplinary Digital Publishing Institute (MDPI)).
Abstract | Links | BibTeX | Tags: Data integration, Data interoperability, Federated information systems, Federated ontology, Graph framework, Interoperability, Knowledge graphs, Knowledge management, Medical computing, Ontology, Ontology's, Ontop, Query processing, Semantic interoperability, Semantic Web, Semantics, Virtual knowledge, virtual reality, Virtualization, Virtualized knowledge graph
@article{fareedi_semantic_2025,
title = {Semantic Fusion of Health Data: Implementing a Federated Virtualized Knowledge Graph Framework Leveraging Ontop System},
author = {A. A. Fareedi and S. Gagnon and A. Ghazawneh and R. Valverde},
url = {https://www.scopus.com/inward/record.uri?eid=2-s2.0-105009278332&doi=10.3390%2ffi17060245&partnerID=40&md5=72bd14d033887f72e7e0c8a6a1451415},
doi = {10.3390/fi17060245},
issn = {19995903 (ISSN)},
year = {2025},
date = {2025-01-01},
journal = {Future Internet},
volume = {17},
number = {6},
publisher = {Multidisciplinary Digital Publishing Institute (MDPI)},
abstract = {Data integration (DI) and semantic interoperability (SI) are critical in healthcare, enabling seamless, patient-centric data sharing across systems to meet the demand for instant, unambiguous access to health information. Federated information systems (FIS) highlight auspicious issues for seamless DI and SI stemming from diverse data sources or models. We present a hybrid ontology-based design science research engineering (ODSRE) methodology that combines design science activities with ontology engineering principles to address the above-mentioned issues. The ODSRE constructs a systematic mechanism leveraging the Ontop virtual paradigm to establish a state-of-the-art federated virtual knowledge graph framework (FVKG) embedded virtualized knowledge graph approach to mitigate the aforementioned challenges effectively. The proposed FVKG helps construct a virtualized data federation leveraging the Ontop semantic query engine that effectively resolves data bottlenecks. Using a virtualized technique, the FVKG helps to reduce data migration, ensures low latency and dynamic freshness, and facilitates real-time access while upholding integrity and coherence throughout the federation system. As a result, we suggest a customized framework for constructing ontological monolithic semantic artifacts, especially in FIS. The proposed FVKG incorporates ontology-based data access (OBDA) to build a monolithic virtualized repository that integrates various ontological-driven artifacts and ensures semantic alignments using schema mapping techniques. © 2025 by the authors.},
note = {Publisher: Multidisciplinary Digital Publishing Institute (MDPI)},
keywords = {Data integration, Data interoperability, Federated information systems, Federated ontology, Graph framework, Interoperability, Knowledge graphs, Knowledge management, Medical computing, Ontology, Ontology's, Ontop, Query processing, Semantic interoperability, Semantic Web, Semantics, Virtual knowledge, virtual reality, Virtualization, Virtualized knowledge graph},
pubstate = {published},
tppubtype = {article}
}
Data integration (DI) and semantic interoperability (SI) are critical in healthcare, enabling seamless, patient-centric data sharing across systems to meet the demand for instant, unambiguous access to health information. Federated information systems (FIS) highlight auspicious issues for seamless DI and SI stemming from diverse data sources or models. We present a hybrid ontology-based design science research engineering (ODSRE) methodology that combines design science activities with ontology engineering principles to address the above-mentioned issues. The ODSRE constructs a systematic mechanism leveraging the Ontop virtual paradigm to establish a state-of-the-art federated virtual knowledge graph framework (FVKG) embedded virtualized knowledge graph approach to mitigate the aforementioned challenges effectively. The proposed FVKG helps construct a virtualized data federation leveraging the Ontop semantic query engine that effectively resolves data bottlenecks. Using a virtualized technique, the FVKG helps to reduce data migration, ensures low latency and dynamic freshness, and facilitates real-time access while upholding integrity and coherence throughout the federation system. As a result, we suggest a customized framework for constructing ontological monolithic semantic artifacts, especially in FIS. The proposed FVKG incorporates ontology-based data access (OBDA) to build a monolithic virtualized repository that integrates various ontological-driven artifacts and ensures semantic alignments using schema mapping techniques. © 2025 by the authors.
3.
Moudoud, H.; Houda, Z. Abou El; Brik, B.
Advancing Privacy and Fairness in Healthcare Using Federated Edge Learning and Blockchain Journal Article
In: IEEE Internet of Things Journal, vol. 12, no. 22, pp. 46129–46137, 2025, ISSN: 23274662 (ISSN).
Abstract | Links | BibTeX | Tags: Artificial intelligence algorithms, Artificial intelligence techniques, Block-chain, Blockchain, cancer diagnosis, Diagnosis, Distributed computer systems, Federated edge learning, Health care, Healthcare, Healthcare systems, Internet of medical thing, Internet of Medical Things (IoMT), Learning systems, Medical computing, Medical data, Network security, Privacy, Sensitive data
@article{moudoudAdvancingPrivacyFairness2025,
title = {Advancing Privacy and Fairness in Healthcare Using Federated Edge Learning and Blockchain},
author = {H. Moudoud and Z. Abou El Houda and B. Brik},
url = {https://www.scopus.com/pages/publications/105012264671?origin=resultslist},
doi = {10.1109/JIOT.2025.3589179},
issn = {23274662 (ISSN)},
year = {2025},
date = {2025-01-01},
journal = {IEEE Internet of Things Journal},
volume = {12},
number = {22},
pages = {46129–46137},
publisher = {Institute of Electrical and Electronics Engineers Inc.},
abstract = {artificial intelligence (AI) has revolutionized many fields, including healthcare. The adoption of AI techniques in critical healthcare tasks, such as cancer diagnosis, holds great promise for revolutionizing the healthcare system. AI algorithms can be trained on vast datasets to recognize patterns, detect anomalies, and provide accurate assessments. However, the lack of realistic and up-to-date medical data poses a significant challenge to the widespread adoption of AI techniques. Additionally, privacy concerns surrounding sensitive medical data, particularly patient health records (PHRs), hinder data sharing among healthcare practitioners. This article aims to address these challenges by proposing a novel framework, entitled SecureMed, that uses federated learning (FL) and Blockchain to preserve privacy in the healthcare system. In particular, SecureMed consists of: 1) a novel distributed architecture that enables secure collaboration among multiple mobile edge computing (MEC)-based Internet of Medical Things (IoMT) devices, while ensuring the privacy of healthcare systems; 2) a fairness-aware FL solution to ensure that model performance is balanced across all participating healthcare institutions, addressing the issue of imbalanced data contributions; 3) a secure multiparty computation (SMPC) protocol to ensure secure aggregation of local model updates; and 4) a blockchain-based reputation model for collaborative FL training. The proposed framework leverages smart contracts to ensure trustworthiness, decentralization, and transparency in the FL process. The experimental results using the CIC IoMT dataset 2024 highlight the promising potential of SecureMed in revolutionizing healthcare systems. © 2014 IEEE.},
keywords = {Artificial intelligence algorithms, Artificial intelligence techniques, Block-chain, Blockchain, cancer diagnosis, Diagnosis, Distributed computer systems, Federated edge learning, Health care, Healthcare, Healthcare systems, Internet of medical thing, Internet of Medical Things (IoMT), Learning systems, Medical computing, Medical data, Network security, Privacy, Sensitive data},
pubstate = {published},
tppubtype = {article}
}
artificial intelligence (AI) has revolutionized many fields, including healthcare. The adoption of AI techniques in critical healthcare tasks, such as cancer diagnosis, holds great promise for revolutionizing the healthcare system. AI algorithms can be trained on vast datasets to recognize patterns, detect anomalies, and provide accurate assessments. However, the lack of realistic and up-to-date medical data poses a significant challenge to the widespread adoption of AI techniques. Additionally, privacy concerns surrounding sensitive medical data, particularly patient health records (PHRs), hinder data sharing among healthcare practitioners. This article aims to address these challenges by proposing a novel framework, entitled SecureMed, that uses federated learning (FL) and Blockchain to preserve privacy in the healthcare system. In particular, SecureMed consists of: 1) a novel distributed architecture that enables secure collaboration among multiple mobile edge computing (MEC)-based Internet of Medical Things (IoMT) devices, while ensuring the privacy of healthcare systems; 2) a fairness-aware FL solution to ensure that model performance is balanced across all participating healthcare institutions, addressing the issue of imbalanced data contributions; 3) a secure multiparty computation (SMPC) protocol to ensure secure aggregation of local model updates; and 4) a blockchain-based reputation model for collaborative FL training. The proposed framework leverages smart contracts to ensure trustworthiness, decentralization, and transparency in the FL process. The experimental results using the CIC IoMT dataset 2024 highlight the promising potential of SecureMed in revolutionizing healthcare systems. © 2014 IEEE.
4.
Fareedi, A. A.; Gagnon, S.; Ghazawneh, A.; Valverde, R.
Semantic Fusion of Health Data: Implementing a Federated Virtualized Knowledge Graph Framework Leveraging Ontop System Journal Article
In: Future Internet, vol. 17, no. 6, 2025, ISSN: 19995903 (ISSN).
Abstract | Links | BibTeX | Tags: Data integration, Data interoperability, Federated information systems, Federated ontology, Graph framework, Interoperability, Knowledge graphs, Knowledge management, Medical computing, Ontology, Ontology's, Ontop, Query processing, Semantic interoperability, Semantic Web, Semantics, Virtual knowledge, virtual reality, Virtualization, Virtualized knowledge graph
@article{fareediSemanticFusionHealth2025a,
title = {Semantic Fusion of Health Data: Implementing a Federated Virtualized Knowledge Graph Framework Leveraging Ontop System},
author = {A. A. Fareedi and S. Gagnon and A. Ghazawneh and R. Valverde},
url = {https://www.scopus.com/pages/publications/105009278332?origin=resultslist},
doi = {10.3390/fi17060245},
issn = {19995903 (ISSN)},
year = {2025},
date = {2025-01-01},
journal = {Future Internet},
volume = {17},
number = {6},
publisher = {Multidisciplinary Digital Publishing Institute (MDPI)},
abstract = {Data integration (DI) and semantic interoperability (SI) are critical in healthcare, enabling seamless, patient-centric data sharing across systems to meet the demand for instant, unambiguous access to health information. Federated information systems (FIS) highlight auspicious issues for seamless DI and SI stemming from diverse data sources or models. We present a hybrid ontology-based design science research engineering (ODSRE) methodology that combines design science activities with ontology engineering principles to address the above-mentioned issues. The ODSRE constructs a systematic mechanism leveraging the Ontop virtual paradigm to establish a state-of-the-art federated virtual knowledge graph framework (FVKG) embedded virtualized knowledge graph approach to mitigate the aforementioned challenges effectively. The proposed FVKG helps construct a virtualized data federation leveraging the Ontop semantic query engine that effectively resolves data bottlenecks. Using a virtualized technique, the FVKG helps to reduce data migration, ensures low latency and dynamic freshness, and facilitates real-time access while upholding integrity and coherence throughout the federation system. As a result, we suggest a customized framework for constructing ontological monolithic semantic artifacts, especially in FIS. The proposed FVKG incorporates ontology-based data access (OBDA) to build a monolithic virtualized repository that integrates various ontological-driven artifacts and ensures semantic alignments using schema mapping techniques. © 2025 by the authors.},
keywords = {Data integration, Data interoperability, Federated information systems, Federated ontology, Graph framework, Interoperability, Knowledge graphs, Knowledge management, Medical computing, Ontology, Ontology's, Ontop, Query processing, Semantic interoperability, Semantic Web, Semantics, Virtual knowledge, virtual reality, Virtualization, Virtualized knowledge graph},
pubstate = {published},
tppubtype = {article}
}
Data integration (DI) and semantic interoperability (SI) are critical in healthcare, enabling seamless, patient-centric data sharing across systems to meet the demand for instant, unambiguous access to health information. Federated information systems (FIS) highlight auspicious issues for seamless DI and SI stemming from diverse data sources or models. We present a hybrid ontology-based design science research engineering (ODSRE) methodology that combines design science activities with ontology engineering principles to address the above-mentioned issues. The ODSRE constructs a systematic mechanism leveraging the Ontop virtual paradigm to establish a state-of-the-art federated virtual knowledge graph framework (FVKG) embedded virtualized knowledge graph approach to mitigate the aforementioned challenges effectively. The proposed FVKG helps construct a virtualized data federation leveraging the Ontop semantic query engine that effectively resolves data bottlenecks. Using a virtualized technique, the FVKG helps to reduce data migration, ensures low latency and dynamic freshness, and facilitates real-time access while upholding integrity and coherence throughout the federation system. As a result, we suggest a customized framework for constructing ontological monolithic semantic artifacts, especially in FIS. The proposed FVKG incorporates ontology-based data access (OBDA) to build a monolithic virtualized repository that integrates various ontological-driven artifacts and ensures semantic alignments using schema mapping techniques. © 2025 by the authors.
5.
Saini, H. K.; Rani, S.; Ouaissa, M.; Ouaissa, M.; Houda, Z. A. El; Moudoud, H.
CRC Press, 2025, ISBN: 978-100364032-5 (ISBN); 978-104107046-7 (ISBN), (Journal Abbreviation: Digit. Forensics in Next-Gener. Internet of Med. Things: Balanc. Secur. and Sustain. Pages: 283 Publication Title: Digit. Forensics in Next-Gener. Internet of Med. Things: Balanc. Secur. and Sustain.).
Abstract | Links | BibTeX | Tags: Case-studies, Computer forensics, Forensic Techniques, Internet of things, Machine data, Medical computing, Medical data, Medical practitioner, Network security, Next generation Internet, Patient data, Real-world, Security challenges, Security solutions, sustainable development
@book{sainiDigitalForensicsNextGeneration2025,
title = {Digital Forensics in Next-Generation Internet of Medical Things: Balancing Security and Sustainability},
author = {H. K. Saini and S. Rani and M. Ouaissa and M. Ouaissa and Z. A. El Houda and H. Moudoud},
url = {https://www.scopus.com/pages/publications/105024400792?origin=resultslist},
doi = {10.1201/9781003640325},
isbn = {978-100364032-5 (ISBN); 978-104107046-7 (ISBN)},
year = {2025},
date = {2025-01-01},
publisher = {CRC Press},
series = {Digital Forensics in Next-Generation Internet of Medical Things: Balancing Security and Sustainability},
abstract = {This book provides a comprehensive exploration of the security challenges and solutions with digital sustainability in the rapidly evolving digital landscape of digital forensics. It explores the details of protecting Internet of Medical Things (IoMT) environments, where the medical data, patient data, and machine data are at high risk with the digital experiences. The book seeks to provide researchers, medical practitioners, and IT specialists with important information. It aims to set the stage for a future in which security and efficiency in IoMT smoothly blend through real-world case studies. Key themes cover IoMT-specific forensic techniques, the difficulties of striking a balance between environmental responsibility and security, and creative solutions that combine the two viewpoints. © 2026 selection and editorial matter, Hemant Kumar Saini, Sita Rani, Mariya Ouaissa, Mariyam Ouaissa, Zakaria Abou El Houda, and Hajar Moudoud. All rights reserved.},
note = {Journal Abbreviation: Digit. Forensics in Next-Gener. Internet of Med. Things: Balanc. Secur. and Sustain.
Pages: 283
Publication Title: Digit. Forensics in Next-Gener. Internet of Med. Things: Balanc. Secur. and Sustain.},
keywords = {Case-studies, Computer forensics, Forensic Techniques, Internet of things, Machine data, Medical computing, Medical data, Medical practitioner, Network security, Next generation Internet, Patient data, Real-world, Security challenges, Security solutions, sustainable development},
pubstate = {published},
tppubtype = {book}
}
This book provides a comprehensive exploration of the security challenges and solutions with digital sustainability in the rapidly evolving digital landscape of digital forensics. It explores the details of protecting Internet of Medical Things (IoMT) environments, where the medical data, patient data, and machine data are at high risk with the digital experiences. The book seeks to provide researchers, medical practitioners, and IT specialists with important information. It aims to set the stage for a future in which security and efficiency in IoMT smoothly blend through real-world case studies. Key themes cover IoMT-specific forensic techniques, the difficulties of striking a balance between environmental responsibility and security, and creative solutions that combine the two viewpoints. © 2026 selection and editorial matter, Hemant Kumar Saini, Sita Rani, Mariya Ouaissa, Mariyam Ouaissa, Zakaria Abou El Houda, and Hajar Moudoud. All rights reserved.
6.
Fareedi, A. A.; Gagnon, S.; Ghazawneh, A.; Valverde, R.
Semantic Fusion of Health Data: Implementing a Federated Virtualized Knowledge Graph Framework Leveraging Ontop System Journal Article
In: Future Internet, vol. 17, no. 6, 2025, ISSN: 19995903 (ISSN).
Abstract | Links | BibTeX | Tags: Data integration, Data interoperability, Federated information systems, Federated ontology, Graph framework, Interoperability, Knowledge graphs, Knowledge management, Medical computing, Ontology, Ontology's, Ontop, Query processing, Semantic interoperability, Semantic Web, Semantics, Virtual knowledge, virtual reality, Virtualization, Virtualized knowledge graph
@article{fareediSemanticFusionHealth2025b,
title = {Semantic Fusion of Health Data: Implementing a Federated Virtualized Knowledge Graph Framework Leveraging Ontop System},
author = {A. A. Fareedi and S. Gagnon and A. Ghazawneh and R. Valverde},
url = {https://www.scopus.com/inward/record.uri?eid=2-s2.0-105009278332&doi=10.3390%2Ffi17060245&partnerID=40&md5=8f53ce5a912bf16f4ac8bb24fb7338bf},
doi = {10.3390/fi17060245},
issn = {19995903 (ISSN)},
year = {2025},
date = {2025-01-01},
journal = {Future Internet},
volume = {17},
number = {6},
abstract = {Data integration (DI) and semantic interoperability (SI) are critical in healthcare, enabling seamless, patient-centric data sharing across systems to meet the demand for instant, unambiguous access to health information. Federated information systems (FIS) highlight auspicious issues for seamless DI and SI stemming from diverse data sources or models. We present a hybrid ontology-based design science research engineering (ODSRE) methodology that combines design science activities with ontology engineering principles to address the above-mentioned issues. The ODSRE constructs a systematic mechanism leveraging the Ontop virtual paradigm to establish a state-of-the-art federated virtual knowledge graph framework (FVKG) embedded virtualized knowledge graph approach to mitigate the aforementioned challenges effectively. The proposed FVKG helps construct a virtualized data federation leveraging the Ontop semantic query engine that effectively resolves data bottlenecks. Using a virtualized technique, the FVKG helps to reduce data migration, ensures low latency and dynamic freshness, and facilitates real-time access while upholding integrity and coherence throughout the federation system. As a result, we suggest a customized framework for constructing ontological monolithic semantic artifacts, especially in FIS. The proposed FVKG incorporates ontology-based data access (OBDA) to build a monolithic virtualized repository that integrates various ontological-driven artifacts and ensures semantic alignments using schema mapping techniques. © 2025 by the authors.},
keywords = {Data integration, Data interoperability, Federated information systems, Federated ontology, Graph framework, Interoperability, Knowledge graphs, Knowledge management, Medical computing, Ontology, Ontology's, Ontop, Query processing, Semantic interoperability, Semantic Web, Semantics, Virtual knowledge, virtual reality, Virtualization, Virtualized knowledge graph},
pubstate = {published},
tppubtype = {article}
}
Data integration (DI) and semantic interoperability (SI) are critical in healthcare, enabling seamless, patient-centric data sharing across systems to meet the demand for instant, unambiguous access to health information. Federated information systems (FIS) highlight auspicious issues for seamless DI and SI stemming from diverse data sources or models. We present a hybrid ontology-based design science research engineering (ODSRE) methodology that combines design science activities with ontology engineering principles to address the above-mentioned issues. The ODSRE constructs a systematic mechanism leveraging the Ontop virtual paradigm to establish a state-of-the-art federated virtual knowledge graph framework (FVKG) embedded virtualized knowledge graph approach to mitigate the aforementioned challenges effectively. The proposed FVKG helps construct a virtualized data federation leveraging the Ontop semantic query engine that effectively resolves data bottlenecks. Using a virtualized technique, the FVKG helps to reduce data migration, ensures low latency and dynamic freshness, and facilitates real-time access while upholding integrity and coherence throughout the federation system. As a result, we suggest a customized framework for constructing ontological monolithic semantic artifacts, especially in FIS. The proposed FVKG incorporates ontology-based data access (OBDA) to build a monolithic virtualized repository that integrates various ontological-driven artifacts and ensures semantic alignments using schema mapping techniques. © 2025 by the authors.
7.
Fareedi, A. A.; Gagnon, S.; Ghazawneh, A.; Valverde, R.
Semantic Fusion of Health Data: Implementing a Federated Virtualized Knowledge Graph Framework Leveraging Ontop System Journal Article
In: Future Internet, vol. 17, no. 6, 2025, ISSN: 19995903 (ISSN).
Abstract | Links | BibTeX | Tags: Data integration, Data interoperability, Federated information systems, Federated ontology, Graph framework, Interoperability, Knowledge graphs, Knowledge management, Medical computing, Ontology, Ontology's, Ontop, Query processing, Semantic interoperability, Semantic Web, Semantics, Virtual knowledge, virtual reality, Virtualization, Virtualized knowledge graph
@article{fareediSemanticFusionHealth2025,
title = {Semantic Fusion of Health Data: Implementing a Federated Virtualized Knowledge Graph Framework Leveraging Ontop System},
author = {A. A. Fareedi and S. Gagnon and A. Ghazawneh and R. Valverde},
url = {https://www.scopus.com/inward/record.uri?eid=2-s2.0-105009278332&doi=10.3390%2ffi17060245&partnerID=40&md5=72bd14d033887f72e7e0c8a6a1451415},
doi = {10.3390/fi17060245},
issn = {19995903 (ISSN)},
year = {2025},
date = {2025-01-01},
journal = {Future Internet},
volume = {17},
number = {6},
publisher = {Multidisciplinary Digital Publishing Institute (MDPI)},
abstract = {Data integration (DI) and semantic interoperability (SI) are critical in healthcare, enabling seamless, patient-centric data sharing across systems to meet the demand for instant, unambiguous access to health information. Federated information systems (FIS) highlight auspicious issues for seamless DI and SI stemming from diverse data sources or models. We present a hybrid ontology-based design science research engineering (ODSRE) methodology that combines design science activities with ontology engineering principles to address the above-mentioned issues. The ODSRE constructs a systematic mechanism leveraging the Ontop virtual paradigm to establish a state-of-the-art federated virtual knowledge graph framework (FVKG) embedded virtualized knowledge graph approach to mitigate the aforementioned challenges effectively. The proposed FVKG helps construct a virtualized data federation leveraging the Ontop semantic query engine that effectively resolves data bottlenecks. Using a virtualized technique, the FVKG helps to reduce data migration, ensures low latency and dynamic freshness, and facilitates real-time access while upholding integrity and coherence throughout the federation system. As a result, we suggest a customized framework for constructing ontological monolithic semantic artifacts, especially in FIS. The proposed FVKG incorporates ontology-based data access (OBDA) to build a monolithic virtualized repository that integrates various ontological-driven artifacts and ensures semantic alignments using schema mapping techniques. © 2025 by the authors.},
keywords = {Data integration, Data interoperability, Federated information systems, Federated ontology, Graph framework, Interoperability, Knowledge graphs, Knowledge management, Medical computing, Ontology, Ontology's, Ontop, Query processing, Semantic interoperability, Semantic Web, Semantics, Virtual knowledge, virtual reality, Virtualization, Virtualized knowledge graph},
pubstate = {published},
tppubtype = {article}
}
Data integration (DI) and semantic interoperability (SI) are critical in healthcare, enabling seamless, patient-centric data sharing across systems to meet the demand for instant, unambiguous access to health information. Federated information systems (FIS) highlight auspicious issues for seamless DI and SI stemming from diverse data sources or models. We present a hybrid ontology-based design science research engineering (ODSRE) methodology that combines design science activities with ontology engineering principles to address the above-mentioned issues. The ODSRE constructs a systematic mechanism leveraging the Ontop virtual paradigm to establish a state-of-the-art federated virtual knowledge graph framework (FVKG) embedded virtualized knowledge graph approach to mitigate the aforementioned challenges effectively. The proposed FVKG helps construct a virtualized data federation leveraging the Ontop semantic query engine that effectively resolves data bottlenecks. Using a virtualized technique, the FVKG helps to reduce data migration, ensures low latency and dynamic freshness, and facilitates real-time access while upholding integrity and coherence throughout the federation system. As a result, we suggest a customized framework for constructing ontological monolithic semantic artifacts, especially in FIS. The proposed FVKG incorporates ontology-based data access (OBDA) to build a monolithic virtualized repository that integrates various ontological-driven artifacts and ensures semantic alignments using schema mapping techniques. © 2025 by the authors.