

de Recherche et d’Innovation
en Cybersécurité et Société
Ernst, M.; Bouchard, S.; Andersen, T.; Orskov, P. T.; Tarp, K.; Lichtenstein, M. B.
Virtual Reality–Based Exposure With 360° Environments for Social Anxiety Disorder: Usability and Feasibility Study Journal Article
In: JMIR Formative Research, vol. 8, 2024, ISSN: 2561326X (ISSN), (Publisher: JMIR Publications Inc.).
Abstract | Links | BibTeX | Tags: 360°, Anxiety, Exposure therapy, interactive, Mixed methods, social anxiety disorder, virtual reality
@article{ernst_virtual_2024,
title = {Virtual Reality–Based Exposure With 360° Environments for Social Anxiety Disorder: Usability and Feasibility Study},
author = {M. Ernst and S. Bouchard and T. Andersen and P. T. Orskov and K. Tarp and M. B. Lichtenstein},
url = {https://www.scopus.com/inward/record.uri?eid=2-s2.0-85207452707&doi=10.2196%2f55679&partnerID=40&md5=603ff828b152a1cdbc241ab7601a43e5},
doi = {10.2196/55679},
issn = {2561326X (ISSN)},
year = {2024},
date = {2024-01-01},
journal = {JMIR Formative Research},
volume = {8},
abstract = {Background: Social anxiety disorder (SAD) is a long-term and overwhelming fear of social situations that can affect work, school, and other daily activities. Although cognitive behavioral therapy is effective, few seek treatment, and many who do start often drop out. This may be due to the component of exposure inherent to cognitive behavioral therapy, where the patient confronts feared stimuli outside the therapist’s office, which they otherwise try to avoid. As an alternative, research has explored the effectiveness of virtual reality (VR)–based exposure therapy with promising results. However, few studies have investigated the feasibility of VR tools using mixed methodologies before assessing their efficacy. Objective: This study aims to assess the usability, feasibility, and presence of four 360° virtual environments and whether these were able to evoke anxiety in patients with SAD. Methods: A total of 10 adult participants with SAD and 10 healthy controls were recruited for 1 experimental session (age range 21-32 y; 12/20, 60% male participants). Questionnaire and interview data were collected and analyzed. A mixed methods triangulation design was applied to analyze and compare the data. Results: Participants with SAD experienced increased anxiety when exposed to VR, and environments were considered relevant and useful as an exposure tool. Participants with SAD reported significantly higher average anxiety levels (P=.01) and peak anxiety levels (P=.01) compared with controls during exposure; however, significant differences in anxiety when accounting for baseline anxiety levels were only found in 2 of 4 environments (P=.01},
note = {Publisher: JMIR Publications Inc.},
keywords = {360°, Anxiety, Exposure therapy, interactive, Mixed methods, social anxiety disorder, virtual reality},
pubstate = {published},
tppubtype = {article}
}
Ernst, M. T.; Nielsen, J. Hyldig; Runge, E.; Bouchard, S.; Clemmensen, L.
Biomarkers in exposure-based treatment of anxiety in virtual reality: a systematic review Journal Article
In: Frontiers in Virtual Reality, vol. 5, 2024, ISSN: 26734192 (ISSN), (Publisher: Frontiers Media SA).
Abstract | Links | BibTeX | Tags: Anxiety, Biomarkers, Exposure therapy, systematic review, virtual reality
@article{ernst_biomarkers_2024,
title = {Biomarkers in exposure-based treatment of anxiety in virtual reality: a systematic review},
author = {M. T. Ernst and J. Hyldig Nielsen and E. Runge and S. Bouchard and L. Clemmensen},
url = {https://www.scopus.com/inward/record.uri?eid=2-s2.0-85197316386&doi=10.3389%2ffrvir.2024.1355082&partnerID=40&md5=500a06f8e6489e75933d79342b606762},
doi = {10.3389/frvir.2024.1355082},
issn = {26734192 (ISSN)},
year = {2024},
date = {2024-01-01},
journal = {Frontiers in Virtual Reality},
volume = {5},
abstract = {Background: A large proportion of individuals with anxiety-related disorders refrain from seeking treatment. This may be because traditional exposure treatments induce anxiety. However, advances in exposure using virtual reality technology may encourage more individuals to seek treatment. Furthermore, using biomarkers with VR-based exposure may enable clinicians to assess anxiety levels objectively and collect data in a naturalistic setting. Methods: Here, we conduct a systematic review of the literature on the use of biomarkers in VR-based exposure treatment for anxiety. Twenty-seven studies were included, with a total of 1046 participants. Results: We found that heart rate was the only biomarker that tentatively could identify changes within (75% of instances) and between sessions (60% of instances). The levels of synchrony between the findings for overall biomarkers and the results from questionnaires showed inconclusive results. Regarding the levels of synchrony between the findings for particular biomarkers and the results from questionnaires, only skin conductance level was highly synchronous for differences between groups (87% of instances). Conclusion: Based on the present review, biomarkers cannot yet be used reliably to distinguish differences in self-reported symptoms of anxiety in VR-based exposure treatments. Copyright © 2024 Ernst, Hyldig Nielsen, Runge, Bouchard and Clemmensen.},
note = {Publisher: Frontiers Media SA},
keywords = {Anxiety, Biomarkers, Exposure therapy, systematic review, virtual reality},
pubstate = {published},
tppubtype = {article}
}
Corno, G.; Villani, D.; Montigny, F.; Pierce, T.; Bouchard, S.; Molgora, S.
The role of perceived social support on pregnant women’s mental health during the COVID-19 pandemic Journal Article
In: Journal of Reproductive and Infant Psychology, vol. 41, no. 5, pp. 488–502, 2023, ISSN: 02646838, (Publisher: Routledge).
Abstract | Links | BibTeX | Tags: adult, Anxiety, article, Canada, coronavirus disease 2019, COVID-19, cross-sectional study, Depression, Edinburgh Postnatal Depression Scale, educational status, female, human, Humans, major clinical study, Mental health, mental stress, Multidimensional Scale of Perceived Social Support, pandemic, Pandemics, postnatal depression, Pregnancy, pregnant woman, Pregnant Women, psychology, questionnaire, Satisfaction with Life Scale, Social Support, State Trait Anxiety Inventory
@article{corno_role_2023,
title = {The role of perceived social support on pregnant women’s mental health during the COVID-19 pandemic},
author = {G. Corno and D. Villani and F. Montigny and T. Pierce and S. Bouchard and S. Molgora},
url = {https://www.scopus.com/inward/record.uri?eid=2-s2.0-85128462603&doi=10.1080%2f02646838.2022.2042799&partnerID=40&md5=aa1b1a6cbd1fab3d6302a31612c86068},
doi = {10.1080/02646838.2022.2042799},
issn = {02646838},
year = {2023},
date = {2023-01-01},
journal = {Journal of Reproductive and Infant Psychology},
volume = {41},
number = {5},
pages = {488–502},
abstract = {Purpose: The present study aimed at investigating which sources of social support best account for pregnant women’s levels of psychological distress and mental well-being during the COVID-19 pandemic. Methods: 274 Italian and Canadian expectant mothers completed an online-based survey including measures of perceived social support (from family, significant other and friends), state anxiety, depressive symptoms, and satisfaction with life. Correlation analyses and amultivariate analysis of covariance were performed to explore how social support from different sources was related to depressive symptoms, state anxiety and satisfaction with life. Results: Different sources of social support contributed to explaining women’s psychological distress and mental well-being. Social support both from family and friends was significantly related to women’s state anxiety and depressive symptoms. Social support from friends was specifically related to women’s satisfaction with life. Conclusion: Our findings endorse the crucial role of perceived social support as a protective factor for pregnant women’s mental health. In the context of the COVID-19 pandemic, our results suggest that support from family seems important in preventing psychological distress, whereas support from friends is also associated with mental well-being. These results may help designing future interventions aimed at improving women’s perinatal mental health in life-threatening conditions. ©, Society for Reproductive and Infant Psychology.},
note = {Publisher: Routledge},
keywords = {adult, Anxiety, article, Canada, coronavirus disease 2019, COVID-19, cross-sectional study, Depression, Edinburgh Postnatal Depression Scale, educational status, female, human, Humans, major clinical study, Mental health, mental stress, Multidimensional Scale of Perceived Social Support, pandemic, Pandemics, postnatal depression, Pregnancy, pregnant woman, Pregnant Women, psychology, questionnaire, Satisfaction with Life Scale, Social Support, State Trait Anxiety Inventory},
pubstate = {published},
tppubtype = {article}
}
Maïano, C.; Morin, A. J. S.; Gagnon, C.; Olivier, E.; Tracey, D.; Craven, R. G.; Bouchard, S.
Validation of an Adapted Version of the Glasgow Anxiety Scale for People with Intellectual Disabilities (GAS-ID) Journal Article
In: Journal of Autism and Developmental Disorders, vol. 53, no. 4, pp. 1560–1572, 2023, ISSN: 01623257, (Publisher: Springer).
Abstract | Links | BibTeX | Tags: Adolescent, adult, Anxiety, anxiety assessment, article, Australia, autism, Autism Spectrum Disorder, Canada, Child, confirmatory factor analysis, controlled study, convergent validity, emotion assessment, English (language), exploratory structural equation modeling, female, French (language), glasgow anxiety scale, human, Humans, instrument validation, Intellectual Disability, intellectual impairment, intelligence quotient, loneliness, major clinical study, male, Psychometrics, psychometry, reliability, reproducibility, Reproducibility of Results, school child, school loneliness scale, self description questionnaire 1, self esteem, self report, self-concept assessment, statistical analysis, validity, Young Adult
@article{maiano_validation_2023,
title = {Validation of an Adapted Version of the Glasgow Anxiety Scale for People with Intellectual Disabilities (GAS-ID)},
author = {C. Maïano and A. J. S. Morin and C. Gagnon and E. Olivier and D. Tracey and R. G. Craven and S. Bouchard},
url = {https://www.scopus.com/inward/record.uri?eid=2-s2.0-85125069450&doi=10.1007%2fs10803-021-05398-7&partnerID=40&md5=7347eb15e719941ce5eca046eb7f4564},
doi = {10.1007/s10803-021-05398-7},
issn = {01623257},
year = {2023},
date = {2023-01-01},
journal = {Journal of Autism and Developmental Disorders},
volume = {53},
number = {4},
pages = {1560–1572},
abstract = {The objective of the study was to validate adapted versions of the Glasgow Anxiety Scale for people with Intellectual Disabilities (GAS-ID) simultaneously developed in English and French. A sample of 361 youth with mild to moderate intellectual disability (ID) (M = 15.78 years) from Australia (English-speaking) and Canada (French-speaking) participated in this study. The results supported the factor validity and reliability, measurement invariance (between English and French versions), a lack of differential items functioning (as a function of youth’s age and ID level, but not sex in the English-Australian sample), temporal stability (over one year interval), and convergent validity (with global self-esteem and school loneliness) of a bi-factor exploratory structural equation modeling representation of the GAS-ID. The present study supports the psychometric properties of the English-Australian and French-Canadian versions of the adapted GAS-ID. © 2022, The Author(s), under exclusive licence to Springer Science+Business Media, LLC, part of Springer Nature.},
note = {Publisher: Springer},
keywords = {Adolescent, adult, Anxiety, anxiety assessment, article, Australia, autism, Autism Spectrum Disorder, Canada, Child, confirmatory factor analysis, controlled study, convergent validity, emotion assessment, English (language), exploratory structural equation modeling, female, French (language), glasgow anxiety scale, human, Humans, instrument validation, Intellectual Disability, intellectual impairment, intelligence quotient, loneliness, major clinical study, male, Psychometrics, psychometry, reliability, reproducibility, Reproducibility of Results, school child, school loneliness scale, self description questionnaire 1, self esteem, self report, self-concept assessment, statistical analysis, validity, Young Adult},
pubstate = {published},
tppubtype = {article}
}
Dugas, M. J.; Marchal, K. Giguère; Cormier, S.; Bouchard, S.; Gouin, J. -P.; Shafran, R.
Pain catastrophizing and worry about health in generalized anxiety disorder Journal Article
In: Clinical Psychology and Psychotherapy, vol. 30, no. 4, pp. 852–861, 2023, ISSN: 10633995, (Publisher: John Wiley and Sons Ltd).
Abstract | Links | BibTeX | Tags: adult, Anxiety, Anxiety disorder, Anxiety Disorders, Catastrophization, catastrophizing, human, Humans, Pain, psychology, uncertainty
@article{dugas_pain_2023,
title = {Pain catastrophizing and worry about health in generalized anxiety disorder},
author = {M. J. Dugas and K. Giguère Marchal and S. Cormier and S. Bouchard and J. -P. Gouin and R. Shafran},
url = {https://www.scopus.com/inward/record.uri?eid=2-s2.0-85150514206&doi=10.1002%2fcpp.2843&partnerID=40&md5=2676de0f5a42bcdaea5f10aa5e8e3f55},
doi = {10.1002/cpp.2843},
issn = {10633995},
year = {2023},
date = {2023-01-01},
journal = {Clinical Psychology and Psychotherapy},
volume = {30},
number = {4},
pages = {852–861},
abstract = {Because the diagnostic criteria of generalized anxiety disorder (GAD) are not tied to specific worry domains (worry is ‘generalized’), research on the content of worry in GAD is lacking. To our knowledge, no study has addressed vulnerability for specific worry topics in GAD. The goal of the current study, a secondary analysis of data from a clinical trial, is to explore the relationship between pain catastrophizing and worry about health in a sample of 60 adults with primary GAD. All data for this study were collected at pretest, prior to randomization to experimental condition in the larger trial. The hypotheses were that (1) pain catastrophizing would be positively related to the severity of GAD, (2) the relationship between pain catastrophizing and the severity of GAD would not be explained by intolerance of uncertainty and psychological rigidity, and (3) pain catastrophizing would be greater in participants reporting worry about health compared to those not reporting worry about health. All hypotheses were confirmed, suggesting that pain catastrophizing may be a threat-specific vulnerability for health-related worry in GAD. The implications of the current findings include a better understanding of the ideographic content of worry, which could help focus treatment interventions for individuals with GAD. © 2023 The Authors. Clinical Psychology & Psychotherapy published by John Wiley & Sons Ltd.},
note = {Publisher: John Wiley and Sons Ltd},
keywords = {adult, Anxiety, Anxiety disorder, Anxiety Disorders, Catastrophization, catastrophizing, human, Humans, Pain, psychology, uncertainty},
pubstate = {published},
tppubtype = {article}
}
Baillot, A.; Brunet, J.; Lemelin, L.; Gabriel, S. A.; Langlois, M. -F.; Tchernof, A.; Biertho, L.; Rabasa-Lhoret, R.; Garneau, P. Y.; Aimé, A.; Bouchard, S.; Romain, A. J.; Bernard, P.
Factors Associated with Excess Skin After Bariatric Surgery: a Mixed-Method Study Journal Article
In: Obesity Surgery, vol. 33, no. 8, pp. 2324–2334, 2023, ISSN: 09608923 (ISSN), (Publisher: Springer).
Abstract | Links | BibTeX | Tags: adult, Alcohol Use Disorders Identification Test, anthropometry, Anxiety, article, asthma, Bariatric Surgery, body dissatisfaction, body image, body mass, Body Mass Index, controlled study, dermatomycosis, Dyadic Adjustment Scale, employment status, excess skin, female, heart disease, Hospital Anxiety and Depression Scale, household income, human, Humans, hypertension, major clinical study, male, Mental health, Middle Aged, Mixed methods, Morbid, morbid obesity, non insulin dependent diabetes mellitus, obesity, physical activity, procedures, psychology, qualitative analysis, quality of life, quantitative analysis, sedentary time, skin irritation, skin malformation, sleep apnea syndromes, social psychology, Social Support, stria, sun exposure
@article{baillot_factors_2023,
title = {Factors Associated with Excess Skin After Bariatric Surgery: a Mixed-Method Study},
author = {A. Baillot and J. Brunet and L. Lemelin and S. A. Gabriel and M. -F. Langlois and A. Tchernof and L. Biertho and R. Rabasa-Lhoret and P. Y. Garneau and A. Aimé and S. Bouchard and A. J. Romain and P. Bernard},
url = {https://www.scopus.com/inward/record.uri?eid=2-s2.0-85163716815&doi=10.1007%2fs11695-023-06698-w&partnerID=40&md5=c86ee43b5f7daf6c350936d38944d013},
doi = {10.1007/s11695-023-06698-w},
issn = {09608923 (ISSN)},
year = {2023},
date = {2023-01-01},
journal = {Obesity Surgery},
volume = {33},
number = {8},
pages = {2324–2334},
abstract = {Purpose: After metabolic and bariatric surgery (MBS), many patients have excess skin (ES), which can cause inconveniences. Identifying factors related to ES quantity and inconveniences is crucial to inform interventions. The aim of this study was to identify sociodemographic, physical, psychosocial, and behavioral factors associated with ES quantity and inconveniences. Materials and Methods: A mixed-method study with a sequential explanatory design was conducted with 124 adults (92% women, M age 46.5 ± 9.9 years, M time post-MBS 34.2 ± 27.6 months). During phase I, ES quantity (arms, abdomen, thighs) and inconveniences and sociodemographic, anthropometric, clinical, and behavioral outcomes were assessed. In phase II, 7 focus groups were performed with 37 participants from phase I. A triangulation protocol was completed to identify convergences, complementarities, and dissonances from quantitative and qualitative data. Results: Quantitative data indicate only ES quantity on arms was associated with ES inconveniences on arms (r =.36, p <.01). Total ES quantity was associated with maximal body mass index (BMI) reached pre-MBS (r =.48, p <.05) and current BMI (r =.35, p <.05). Greater ES inconvenience was associated with higher social physique anxiety and age (R 2 =.50, p <.01). Qualitative data were summarized into 4 themes: psychosocial experiences living with ES, physical ailments due to ES, essential support and unmet needs, and beliefs of ES quantity causes. Conclusion: Measured ES quantity is related to higher BMI, but not reported inconveniences. Greater self-reported ES quantity and inconveniences were associated with body image concerns. Graphical Abstract: [Figure not available: see fulltext.] © 2023, The Author(s), under exclusive licence to Springer Science+Business Media, LLC, part of Springer Nature.},
note = {Publisher: Springer},
keywords = {adult, Alcohol Use Disorders Identification Test, anthropometry, Anxiety, article, asthma, Bariatric Surgery, body dissatisfaction, body image, body mass, Body Mass Index, controlled study, dermatomycosis, Dyadic Adjustment Scale, employment status, excess skin, female, heart disease, Hospital Anxiety and Depression Scale, household income, human, Humans, hypertension, major clinical study, male, Mental health, Middle Aged, Mixed methods, Morbid, morbid obesity, non insulin dependent diabetes mellitus, obesity, physical activity, procedures, psychology, qualitative analysis, quality of life, quantitative analysis, sedentary time, skin irritation, skin malformation, sleep apnea syndromes, social psychology, Social Support, stria, sun exposure},
pubstate = {published},
tppubtype = {article}
}
Belleville, G.; Ouellet, M. -C.; Békés, V.; Lebel, J.; Morin, C. M.; Bouchard, S.; Guay, S.; Bergeron, N.; Ghosh, S.; Campbell, T.; Macmaster, F. P.
In: Behavior Therapy, vol. 54, no. 2, pp. 230–246, 2023, ISSN: 00057894 (ISSN), (Publisher: Elsevier Inc.).
Abstract | Links | BibTeX | Tags: adult, Anxiety, article, clinical effectiveness, clinical feature, cognitive behavioral therapy, controlled study, Depression, disaster, Disasters, disease severity, e-mental health, female, human, Humans, insomnia, Internet-Based Intervention, major clinical study, male, Middle Aged, natural disaster, physical disability, Post-Traumatic, posttraumatic stress disorder, psychotherapist, PTSD, randomized controlled trial, risk factor, Sleep Initiation and Maintenance Disorders, Stress Disorders, telepsychotherapy, treatment outcome, wildfire
@article{belleville_efficacy_2023,
title = {Efficacy of a Therapist-Assisted Self-Help Internet-Based Intervention Targeting PTSD, Depression, and Insomnia Symptoms After a Disaster: A Randomized Controlled Trial},
author = {G. Belleville and M. -C. Ouellet and V. Békés and J. Lebel and C. M. Morin and S. Bouchard and S. Guay and N. Bergeron and S. Ghosh and T. Campbell and F. P. Macmaster},
url = {https://www.scopus.com/inward/record.uri?eid=2-s2.0-85140981202&doi=10.1016%2fj.beth.2022.08.004&partnerID=40&md5=261383919bbdaa149ac0eeb6d3317fc0},
doi = {10.1016/j.beth.2022.08.004},
issn = {00057894 (ISSN)},
year = {2023},
date = {2023-01-01},
journal = {Behavior Therapy},
volume = {54},
number = {2},
pages = {230–246},
abstract = {This study aimed at evaluating the efficacy of an online CBT intervention with limited therapist contact targeting a range of posttraumatic symptoms among evacuees from the 2016 Fort McMurray wildfires. One hundred and thirty-six residents of Fort McMurray who reported either moderate PTSD symptoms (PCL-5 ≥ 23) or mild PTSD symptoms (PCL-5 ≥ 10) with moderate depression (PHQ-9 ≥ 10) or subthreshold insomnia symptoms (ISI ≥ 8) were randomized either to a treatment (n = 69) or a waitlist condition (n = 67). Participants were on average 45 years old, and mostly identified as White (82%) and as women (76%). Primary outcomes were PTSD, depression, and insomnia symptoms. Secondary outcomes were anxiety symptoms and disability. Significant Assessment Time × Treatment Condition interactions were observed on all outcomes, indicating that access to the treatment led to a decrease in posttraumatic stress (F[1,117.04] = 12.128},
note = {Publisher: Elsevier Inc.},
keywords = {adult, Anxiety, article, clinical effectiveness, clinical feature, cognitive behavioral therapy, controlled study, Depression, disaster, Disasters, disease severity, e-mental health, female, human, Humans, insomnia, Internet-Based Intervention, major clinical study, male, Middle Aged, natural disaster, physical disability, Post-Traumatic, posttraumatic stress disorder, psychotherapist, PTSD, randomized controlled trial, risk factor, Sleep Initiation and Maintenance Disorders, Stress Disorders, telepsychotherapy, treatment outcome, wildfire},
pubstate = {published},
tppubtype = {article}
}
Cinalioglu, K.; Lavín, P.; Bein, M.; Lesage, M.; Gruber, J.; Se, J.; Bukhari, S.; Sasi, N.; Noble, H.; Andree-Bruneau, M.; Launay, C.; Sanders, J.; Gauthier, S.; Rosa, P.; Lifshitz, M.; Battistini, B. J.; Beauchet, O.; Khoury, B.; Bouchard, S.; Fallavollita, P.; Vahia, I.; Rej, S.; Sekhon, H.
Effects of virtual reality guided meditation in older adults: the protocol of a pilot randomized controlled trial Journal Article
In: Frontiers in Psychology, vol. 14, 2023, ISSN: 16641078 (ISSN), (Publisher: Frontiers Media SA).
Abstract | Links | BibTeX | Tags: Anxiety, Depression, meditation, mindfulness, older adults, virtual reality
@article{cinalioglu_effects_2023,
title = {Effects of virtual reality guided meditation in older adults: the protocol of a pilot randomized controlled trial},
author = {K. Cinalioglu and P. Lavín and M. Bein and M. Lesage and J. Gruber and J. Se and S. Bukhari and N. Sasi and H. Noble and M. Andree-Bruneau and C. Launay and J. Sanders and S. Gauthier and P. Rosa and M. Lifshitz and B. J. Battistini and O. Beauchet and B. Khoury and S. Bouchard and P. Fallavollita and I. Vahia and S. Rej and H. Sekhon},
url = {https://www.scopus.com/inward/record.uri?eid=2-s2.0-85167920206&doi=10.3389%2ffpsyg.2023.1083219&partnerID=40&md5=e5bae2e2f286bca584f893ad57387285},
doi = {10.3389/fpsyg.2023.1083219},
issn = {16641078 (ISSN)},
year = {2023},
date = {2023-01-01},
journal = {Frontiers in Psychology},
volume = {14},
abstract = {Background: Virtual reality (VR) based meditation has been shown to help increase relaxation and decrease anxiety and depression in younger adults. However, this has not been studied in Randomized Controlled Trials (RCT) in the older adult population. The aim of this RCT is to assess the feasibility and acceptability of a VR-guided meditation intervention for community-dwelling older adults and its effect on stress and mental health. Methods: We will recruit 30 participants aged ≥ 60 years, whose perceived stress score (PSS) is > 14 (moderate stress), and randomize them 1:1 to the intervention or control waitlist group. The intervention will involve exposure to eight 15-min VR-guided meditation sessions distributed twice weekly for 4-weeks. Two modalities will be offered: in-home and at the hospital. Data analysis: Baseline and post-intervention assessments will evaluate perceived stress, anxiety, depression, sleep quality, quality of life, and mindfulness skills. Analyses will employ mixed methods repeated ANOVA tests. Qualitative analyses through semi-structured interviews and participant observation will be used to assess participants’ experiences. Study outcomes include: (A) feasibility and acceptability compared to a waitlist control (B) stress, using the Perceived Stress Scale (PSS); (C) anxiety, and depression, using the Generalized Anxiety Disorder-7 (GAD-7) and Patient Health Questionnaire-9 (PHQ-9); (D) insomnia, quality of life and mindfulness skills, using the Athens Insomnia Scale (AIS), Quality of Life Questionnaire (EQ-5D-5L) and Five Facets Mindfulness Questionnaire Short Forms (FFMQ-SF), respectively. We will also measure immersive tendencies, sickness and sense of presence using the Simulator Sickness Questionnaire (SSQ) and the Presence Questionnaire (PQ). Discussion: Virtual reality-guided meditation could be an acceptable, feasible, safe, and cost-effective novel alternative health intervention for improving older adults’ mental health. Clinical trial registration: NCT05315609 at https://clinicaltrials.gov. Copyright © 2023 Cinalioglu, Lavín, Bein, Lesage, Gruber, Se, Bukhari, Sasi, Noble, Andree-Bruneau, Launay, Sanders, Gauthier, Rosa, Lifshitz, Battistini, Beauchet, Khoury, Bouchard, Fallavollita, Vahia, Rej and Sekhon.},
note = {Publisher: Frontiers Media SA},
keywords = {Anxiety, Depression, meditation, mindfulness, older adults, virtual reality},
pubstate = {published},
tppubtype = {article}
}
Du, K. Le; Septans, A. -L.; Maloisel, F.; Vanquaethem, H.; Schmitt, A.; Goff, M. Le; Clavert, A.; Zinger, M.; Bourgeois, H.; Dupuis, O.; Denis, F.; Bouchard, S.
In: Journal of Medical Internet Research, vol. 25, 2023, ISSN: 14388871 (ISSN), (Publisher: JMIR Publications Inc.).
Abstract | Links | BibTeX | Tags: 80 and over, Adolescent, adult, aged, alprazolam, Anxiety, article, Biopsy, blood pressure measurement, Bone Marrow, bone marrow biopsy, clinical trial, controlled study, demographics, digital health, digital therapeutics, Distraction, Effectiveness, efficacy, eHealth, female, follow up, head-mounted display, hematologic disease, human, human tissue, Humans, hypertension, imagery, imaginary, imagination, Immersive environment, Intention to Treat Analysis, interactive environment, leukemia, lidocaine, local anesthesia, lymphoma, major clinical study, male, medical procedure, Meopa, Middle Aged, monoclonal immunoglobulinemia, multicenter study, myelodysplastic syndrome, myeloma, myeloproliferative disorder, myeloproliferative neoplasm, nitrous oxide plus oxygen, open study, Pain, pain intensity, pain measurement, paracetamol, phase 3 clinical trial, prospective study, questionnaire, randomized controlled trial, RCT, relaxation training, safety, satisfaction, solid malignant neoplasm, State Trait Anxiety Inventory, very elderly, virtual reality, visual analog scale, VR, Young Adult
@article{le_du_new_2023,
title = {A New Option for Pain Prevention Using a Therapeutic Virtual Reality Solution for Bone Marrow Biopsy (REVEH Trial): Open-Label, Randomized, Multicenter, Phase 3 Study},
author = {K. Le Du and A. -L. Septans and F. Maloisel and H. Vanquaethem and A. Schmitt and M. Le Goff and A. Clavert and M. Zinger and H. Bourgeois and O. Dupuis and F. Denis and S. Bouchard},
url = {https://www.scopus.com/inward/record.uri?eid=2-s2.0-85148250546&doi=10.2196%2f38619&partnerID=40&md5=e27bfbd3d4c42f8850daf70bdf60b384},
doi = {10.2196/38619},
issn = {14388871 (ISSN)},
year = {2023},
date = {2023-01-01},
journal = {Journal of Medical Internet Research},
volume = {25},
abstract = {Background: Evidence regarding the analgesic effect of distraction through immersion in virtual reality (VR) for care-induced pain has been documented in several phase 2 trials, but comparison with standard treatments in large, randomized studies is needed. Objective: In this open-label, multicenter, randomized, phase 3 trial, we evaluated the safety and efficacy of a novel VR therapy solution for distraction in the context of bone marrow biopsy. Methods: Bliss is a VR software with 4 imaginary interactive environments in 3 dimensions with binaural sound (head-mounted display). Efficacy regarding pain intensity was evaluated using a visual analog scale (VAS; score from 0 to 10) immediately after the biopsy. Secondary end points were anxiety and tolerance. Modified intention-to-treat analysis was performed. Results: Overall, 126 patients with previously documented untreated or suspected malignant hemopathy between September 6, 2018, and May 18, 2020, were randomly assigned in a 1:1 ratio to receive pain prevention with a mixture of nitrous oxide/oxygen (MEOPA; n=63) or VR (n=63) before and during the bone marrow biopsy. We excluded 8 patients from the final analysis (3 in the MEOPA group and 5 in the VR group). All patients received local anesthesia (lidocaine) before biopsy. Follow-up was limited to 1 month after the biopsy. Participants' median age was 65.5 (range 18-87) years, and 54.2% (64/118) of patients were male. The average pain intensity was 3.5 (SD 2.6, 95% CI -1.6 to 8.6) for the MEOPA group and 3.0 (SD 2.4, 95% CI -1.7 to 7.7) for the VR group, without any significant differences in age, sex, center, and hemopathy (P=.26). Concerning anxiety, 67.5% (79/117; fear of pain questionnaire) of the patients were afraid before the biopsy, and anxiety scores were moderate to very high in 26.3% (30/114; revised Spielberger State-Trait Anxiety Inventory questionnaire) of the patients before the biopsy and 9.0% (10/114) after the biopsy for all patients, without a significant difference between the 2 groups (P=.83). Immersion in VR was well tolerated by the majority (54/57, 95%) of patients in the VR group. Conclusions: The intensity of pain did not significantly differ between both arms. VR was well tolerated, and the satisfaction of patients, nurses, and physicians was very high. VR could be an alternative treatment in case of contraindication or intolerance to MEOPA. © 2023 Journal of Medical Internet Research. All rights reserved.},
note = {Publisher: JMIR Publications Inc.},
keywords = {80 and over, Adolescent, adult, aged, alprazolam, Anxiety, article, Biopsy, blood pressure measurement, Bone Marrow, bone marrow biopsy, clinical trial, controlled study, demographics, digital health, digital therapeutics, Distraction, Effectiveness, efficacy, eHealth, female, follow up, head-mounted display, hematologic disease, human, human tissue, Humans, hypertension, imagery, imaginary, imagination, Immersive environment, Intention to Treat Analysis, interactive environment, leukemia, lidocaine, local anesthesia, lymphoma, major clinical study, male, medical procedure, Meopa, Middle Aged, monoclonal immunoglobulinemia, multicenter study, myelodysplastic syndrome, myeloma, myeloproliferative disorder, myeloproliferative neoplasm, nitrous oxide plus oxygen, open study, Pain, pain intensity, pain measurement, paracetamol, phase 3 clinical trial, prospective study, questionnaire, randomized controlled trial, RCT, relaxation training, safety, satisfaction, solid malignant neoplasm, State Trait Anxiety Inventory, very elderly, virtual reality, visual analog scale, VR, Young Adult},
pubstate = {published},
tppubtype = {article}
}
Sekhon, H.; Lavin, P.; Vacaflor, B.; Rigas, C.; Cinalioglu, K.; Su, C. -L.; Bodenstein, K.; Dikaios, E.; Goodman, A.; Raymond, F. C.; Ibrahim, M.; Bein, M.; Gruber, J.; Se, J.; Sasi, N.; Walsh, C.; Nazar, R.; Hanganu, C.; Berkani, S.; Royal, I.; Schiavetto, A.; Looper, K.; Launay, C.; McDonald, E. G.; Seitz, D.; Kumar, S.; Beauchet, O.; Khoury, B.; Bouchard, S.; Battistini, B.; Fallavollita, P.; Miresco, M.; Bruneau, M. -A.; Vahia, I.; Bukhari, S.; Rej, S.
Isolating together during COVID-19: Results from the Telehealth Intervention Program for older adults Journal Article
In: Frontiers in Medicine, vol. 9, 2022, ISSN: 2296858X, (Publisher: Frontiers Media S.A.).
Abstract | Links | BibTeX | Tags: aged, Anxiety, article, cohort analysis, controlled study, coronavirus disease 2019, demographics, Depression, Fear, female, human, longitudinal study, major clinical study, male, Patient Health Questionnaire 9, physiological stress, prospective study, Quebec, telehealth
@article{sekhon_isolating_2022,
title = {Isolating together during COVID-19: Results from the Telehealth Intervention Program for older adults},
author = {H. Sekhon and P. Lavin and B. Vacaflor and C. Rigas and K. Cinalioglu and C. -L. Su and K. Bodenstein and E. Dikaios and A. Goodman and F. C. Raymond and M. Ibrahim and M. Bein and J. Gruber and J. Se and N. Sasi and C. Walsh and R. Nazar and C. Hanganu and S. Berkani and I. Royal and A. Schiavetto and K. Looper and C. Launay and E. G. McDonald and D. Seitz and S. Kumar and O. Beauchet and B. Khoury and S. Bouchard and B. Battistini and P. Fallavollita and M. Miresco and M. -A. Bruneau and I. Vahia and S. Bukhari and S. Rej},
url = {https://www.scopus.com/inward/record.uri?eid=2-s2.0-85140408885&doi=10.3389%2ffmed.2022.948506&partnerID=40&md5=914f535ebf7ead4bbacb04ee66f75e17},
doi = {10.3389/fmed.2022.948506},
issn = {2296858X},
year = {2022},
date = {2022-01-01},
journal = {Frontiers in Medicine},
volume = {9},
abstract = {Background: A pressing challenge during the COVID-19 pandemic and beyond is to provide accessible and scalable mental health support to isolated older adults in the community. The Telehealth Intervention Program for Older Adults (TIP-OA) is a large-scale, volunteer-based, friendly telephone support program designed to address this unmet need. Methods: A prospective cohort study of 112 TIP-OA participants aged ≥60 years old was conducted in Quebec, Canada (October 2020–June 2021). The intervention consisted of weekly friendly phone calls from trained volunteers. The primary outcome measures included changes in scores of stress, depression, anxiety, and fear surrounding COVID-19, assessed at baseline, 4 and 8-weeks. Additional subgroup analyses were performed with participants with higher baseline scores. Results: The subgroup of participants with higher baseline depression scores (PHQ9 ≥10) had significant improvements in depression scores over the 8-week period measured [mean change score = −2.27 (±4.76), 95%CI (−3.719, −0.827)},
note = {Publisher: Frontiers Media S.A.},
keywords = {aged, Anxiety, article, cohort analysis, controlled study, coronavirus disease 2019, demographics, Depression, Fear, female, human, longitudinal study, major clinical study, male, Patient Health Questionnaire 9, physiological stress, prospective study, Quebec, telehealth},
pubstate = {published},
tppubtype = {article}
}