Slide
Centre Interdisciplinaire
de Recherche et d’Innovation
en Cybersécurité et Société
de Recherche et d’Innovation
en Cybersécurité et Société
1.
Rigas, C.; Lavin, P.; Su, C. -L.; Hassan, M.; Cinalioglu, K.; Vacaflor, B.; Dikaios, E.; Goodman, A.; Ibrahim, M.; Gruber, J.; Se, J.; Sasi, N.; Nazar, R.; Bodenstein, K.; Elbaz, S.; Fajzel, H.; Berkani, S.; Hanganu, C.; Noble, H.; Looper, K.; Bouchard, S.; Seitz, D.; Kumar, S.; Beauchet, O.; Launay, C.; McDonald, E.; Khoury, B.; Ryder, A.; Battistini, B.; Fallavollita, P.; Vahia, I.; Sekhon, H.; Bukhari, S.; Rej, S.
In: BMC Psychiatry, vol. 26, no. 1, 2026, ISSN: 1471244X (ISSN).
Abstract | Links | BibTeX | Tags: 80 and over, adult, aged, Anxiety, article, clinical outcome, clinician, cohort analysis, coronavirus disease 2019, COVID-19, demographics, Depression, female, Generalized Anxiety Disorder-7, Geriatric mental health, health hazard, health program, human, human experiment, Humans, informed consent, male, Mental health, Mental Health Teletherapy, mental stress, older adults, Patient Health Questionnaire 9, Perceived Stress Scale, physiological stress, prediction, Predictors of treatment response, Prospective Studies, prospective study, Psychological, psychology, SARS-CoV-2, secondary analysis, Severe acute respiratory syndrome coronavirus 2, Social isolation, social worker, Stress, telehealth, Telemedicine, teletherapy, Therapy, treatment response, very elderly, Volunteer-based intervention
@article{rigasOptimizingFutureTelehealth2026,
title = {Optimizing future Telehealth mental health programs: a secondary analysis of a prospective cohort study to identify key predictors of intervention response in the Telehealth intervention program for older adults (TIP-OA)},
author = {C. Rigas and P. Lavin and C. -L. Su and M. Hassan and K. Cinalioglu and B. Vacaflor and E. Dikaios and A. Goodman and M. Ibrahim and J. Gruber and J. Se and N. Sasi and R. Nazar and K. Bodenstein and S. Elbaz and H. Fajzel and S. Berkani and C. Hanganu and H. Noble and K. Looper and S. Bouchard and D. Seitz and S. Kumar and O. Beauchet and C. Launay and E. McDonald and B. Khoury and A. Ryder and B. Battistini and P. Fallavollita and I. Vahia and H. Sekhon and S. Bukhari and S. Rej},
url = {https://www.scopus.com/pages/publications/105038539121?origin=resultslist},
doi = {10.1186/s12888-025-07688-1},
issn = {1471244X (ISSN)},
year = {2026},
date = {2026-01-01},
journal = {BMC Psychiatry},
volume = {26},
number = {1},
publisher = {BioMed Central Ltd},
abstract = {Background: The Telehealth Intervention Program for Older Adults (TIP-OA) was a volunteer-based phone support program for to older adults during the COVID-19 pandemic. While volunteer-based phone programs can be effective in providing mental health support, there is limited data on the predictors of response to such interventions. This study aimed to examine clinical and demographic predictors of response to the TIP-OA intervention among older adults. Methods: This secondary analysis of a prospective cohort study included 82 TIP-OA users who expressed interest in the program’s research component, met inclusion criteria, and provided informed consent. Participants completed both baseline and 8-week assessments or had 4-week data carried forward using the last observation carried forward (LOCF) method. The intervention consisted of weekly supportive phone calls over eight weeks. Baseline mental health risk level was assessed by clinicians during intake and categorized as low, medium, or high based on symptom severity within specific symptom categories. Associations between baseline risk level and changes in stress (primary outcome), depression, and anxiety (secondary outcomes) were examined. The primary outcome was measured by the Perceived Stress Scale (PSS; scores ranging from 0 (never) to 4 (very often)). Secondary outcomes were measured by the Patient Health Questionnaire-9 (PHQ-9; scores ranging from 0 (not at all) to 3 (nearly every day)), and the Generalized Anxiety Disorder-7 scale (GAD-7; scores can range from 0 (not at all sure) to 3 (nearly every day)). Results: At 8 -week follow-up assessment, participants with higher baseline risk levels showed greater reductions in stress (mean difference in Perceived Stress Scale reduction by 2.13, (F(1,77) = 2.82},
keywords = {80 and over, adult, aged, Anxiety, article, clinical outcome, clinician, cohort analysis, coronavirus disease 2019, COVID-19, demographics, Depression, female, Generalized Anxiety Disorder-7, Geriatric mental health, health hazard, health program, human, human experiment, Humans, informed consent, male, Mental health, Mental Health Teletherapy, mental stress, older adults, Patient Health Questionnaire 9, Perceived Stress Scale, physiological stress, prediction, Predictors of treatment response, Prospective Studies, prospective study, Psychological, psychology, SARS-CoV-2, secondary analysis, Severe acute respiratory syndrome coronavirus 2, Social isolation, social worker, Stress, telehealth, Telemedicine, teletherapy, Therapy, treatment response, very elderly, Volunteer-based intervention},
pubstate = {published},
tppubtype = {article}
}
Background: The Telehealth Intervention Program for Older Adults (TIP-OA) was a volunteer-based phone support program for to older adults during the COVID-19 pandemic. While volunteer-based phone programs can be effective in providing mental health support, there is limited data on the predictors of response to such interventions. This study aimed to examine clinical and demographic predictors of response to the TIP-OA intervention among older adults. Methods: This secondary analysis of a prospective cohort study included 82 TIP-OA users who expressed interest in the program’s research component, met inclusion criteria, and provided informed consent. Participants completed both baseline and 8-week assessments or had 4-week data carried forward using the last observation carried forward (LOCF) method. The intervention consisted of weekly supportive phone calls over eight weeks. Baseline mental health risk level was assessed by clinicians during intake and categorized as low, medium, or high based on symptom severity within specific symptom categories. Associations between baseline risk level and changes in stress (primary outcome), depression, and anxiety (secondary outcomes) were examined. The primary outcome was measured by the Perceived Stress Scale (PSS; scores ranging from 0 (never) to 4 (very often)). Secondary outcomes were measured by the Patient Health Questionnaire-9 (PHQ-9; scores ranging from 0 (not at all) to 3 (nearly every day)), and the Generalized Anxiety Disorder-7 scale (GAD-7; scores can range from 0 (not at all sure) to 3 (nearly every day)). Results: At 8 -week follow-up assessment, participants with higher baseline risk levels showed greater reductions in stress (mean difference in Perceived Stress Scale reduction by 2.13, (F(1,77) = 2.82
2.
Clemmensen, L.; Bouchard, S.; Rasmussen, J.; Holmberg, T. T.; Nielsen, J. H.; Jepsen, J. R. Mø.; Lichtenstein, M. B.
In: BMC Psychiatry, vol. 20, no. 1, 2020, ISSN: 1471244X, (Publisher: BioMed Central).
Abstract | Links | BibTeX | Tags: adult, Anxiety, article, clinical effectiveness, cognitive behavioral therapy, controlled study, exposure, follow up, health program, human, Humans, in vivo study, outcome assessment, phobia, psychologist, questionnaire, randomized controlled trial, relaxation training, Social, Social Interaction Anxiety Scale, social phobia, treatment outcome, virtual reality, virtual reality exposure therapy, Young Adult
@article{clemmensen_study_2020,
title = {Study protocol: Exposure in virtual reality for social anxiety disorder-a randomized controlled superiority trial comparing cognitive behavioral therapy with virtual reality based exposure to cognitive behavioral therapy with in vivo exposure},
author = {L. Clemmensen and S. Bouchard and J. Rasmussen and T. T. Holmberg and J. H. Nielsen and J. R. Mø. Jepsen and M. B. Lichtenstein},
url = {https://www.scopus.com/inward/record.uri?eid=2-s2.0-85078711155&doi=10.1186%2fs12888-020-2453-4&partnerID=40&md5=28b076f10bf189f7c90b8bed4c719200},
doi = {10.1186/s12888-020-2453-4},
issn = {1471244X},
year = {2020},
date = {2020-01-01},
journal = {BMC Psychiatry},
volume = {20},
number = {1},
publisher = {BioMed Central},
abstract = {Background: Social Anxiety Disorder (SAD) is characterized by an intense fear of negative judgement by others. Cognitive Behavioral Therapy (CBT) is recommended for treatment, but a substantial part of individuals with SAD either do not seek treatment or drop-out. CBT with Virtual Reality (VR)-based exposure has several advantages compared to traditional exposure methods, mainly due to increased control of situational elements. The aim of the current study is to develop a CBT program containing VR-based exposure. The intervention is targeted to adult patients suffering from SAD and treatment effect will be assessed by changes in SAD symptoms. Methods: This article describes the study protocol of a Randomized Controlled Trial with three arms: 1) CBT with VR exposure based on 360° videos 2) CBT with in vivo exposure and 3) VR relaxation therapy. There will be 30 participants in each arm with a crossover at the end of the treatment period during which the participants in the third group will be randomly re-Allocated to one of the two former groups. The treatment program consists of 10 weekly individual sessions with a psychologist, and a six month follow-up consisting of a questionnaire. The primary outcome measure is reduction in SAD symptoms which will be assessed with the Social Interaction Anxiety Scale (SIAS). Discussion: There are currently no published studies on CBT with VR exposure based on 360° videos for SAD treatment. Furthermore, the current study will be the first Danish SAD treatment program that includes VR technology. Trial registration: clinicaltrials.gov (NCT03973541) June 3rd 2019. © 2020 The Author(s).},
note = {Publisher: BioMed Central},
keywords = {adult, Anxiety, article, clinical effectiveness, cognitive behavioral therapy, controlled study, exposure, follow up, health program, human, Humans, in vivo study, outcome assessment, phobia, psychologist, questionnaire, randomized controlled trial, relaxation training, Social, Social Interaction Anxiety Scale, social phobia, treatment outcome, virtual reality, virtual reality exposure therapy, Young Adult},
pubstate = {published},
tppubtype = {article}
}
Background: Social Anxiety Disorder (SAD) is characterized by an intense fear of negative judgement by others. Cognitive Behavioral Therapy (CBT) is recommended for treatment, but a substantial part of individuals with SAD either do not seek treatment or drop-out. CBT with Virtual Reality (VR)-based exposure has several advantages compared to traditional exposure methods, mainly due to increased control of situational elements. The aim of the current study is to develop a CBT program containing VR-based exposure. The intervention is targeted to adult patients suffering from SAD and treatment effect will be assessed by changes in SAD symptoms. Methods: This article describes the study protocol of a Randomized Controlled Trial with three arms: 1) CBT with VR exposure based on 360° videos 2) CBT with in vivo exposure and 3) VR relaxation therapy. There will be 30 participants in each arm with a crossover at the end of the treatment period during which the participants in the third group will be randomly re-Allocated to one of the two former groups. The treatment program consists of 10 weekly individual sessions with a psychologist, and a six month follow-up consisting of a questionnaire. The primary outcome measure is reduction in SAD symptoms which will be assessed with the Social Interaction Anxiety Scale (SIAS). Discussion: There are currently no published studies on CBT with VR exposure based on 360° videos for SAD treatment. Furthermore, the current study will be the first Danish SAD treatment program that includes VR technology. Trial registration: clinicaltrials.gov (NCT03973541) June 3rd 2019. © 2020 The Author(s).