@article{du_sert_virtual_2018,

title = {Virtual reality therapy for refractory auditory verbal hallucinations in schizophrenia: A pilot clinical trial},

author = {O. P. Sert and S. Potvin and O. Lipp and L. Dellazizzo and M. Laurelli and R. Breton and P. Lalonde and K. Phraxayavong and K. O'Connor and J. -F. Pelletier and T. Boukhalfi and P. Renaud and A. Dumais},

url = {https://www.scopus.com/inward/record.uri?eid=2-s2.0-85042420594&doi=10.1016%2fj.schres.2018.02.031&partnerID=40&md5=fe98669ecfdfb69d05cc9ebb58fecdcc},

doi = {10.1016/j.schres.2018.02.031},

issn = {09209964},

year  = {2018},

date = {2018-01-01},

journal = {Schizophrenia Research},

volume = {197},

pages = {176–181},

abstract = {Schizophrenia is a chronic and severe mental illness that poses significant challenges. While many pharmacological and psychosocial interventions are available, many treatment-resistant schizophrenia patients continue to suffer from persistent psychotic symptoms, notably auditory verbal hallucinations (AVH), which are highly disabling. This unmet clinical need requires new innovative treatment options. Recently, a psychological therapy using computerized technology has shown large therapeutic effects on AVH severity by enabling patients to engage in a dialogue with a computerized representation of their voices. These very promising results have been extended by our team using immersive virtual reality (VR). Our study was a 7-week phase-II, randomized, partial cross-over trial. Nineteen schizophrenia patients with refractory AVH were recruited and randomly allocated to either VR-assisted therapy (VRT) or treatment-as-usual (TAU). The group allocated to TAU consisted of antipsychotic treatment and usual meetings with clinicians. The TAU group then received a delayed 7 weeks of VRT. A follow-up was ensured 3 months after the last VRT therapy session. Changes in psychiatric symptoms, before and after TAU or VRT, were assessed using a linear mixed-effects model. Our findings showed that VRT produced significant improvements in AVH severity, depressive symptoms and quality of life that lasted at the 3-month follow-up period. Consistent with previous research, our results suggest that VRT might be efficacious in reducing AVH related distress. The therapeutic effects of VRT on the distress associated with the voices were particularly prominent (d = 1.2). VRT is a highly novel and promising intervention for refractory AVH in schizophrenia. © 2018},

note = {Publisher: Elsevier B.V.},

keywords = {adult, article, auditory hallucination, auditory verbal hallucination, clinical article, clinical effectiveness, computer assisted therapy, Computer-Assisted, controlled study, Cross-Over Studies, crossover procedure, disease severity, distress syndrome, female, follow up, Follow-Up Studies, hallucination, Hallucinations, human, Humans, male, Middle Aged, neuroleptic agent, outcome assessment, Outcome Assessment (Health Care), phase 2 clinical trial, physiology, Pilot Projects, pilot study, priority journal, procedures, psychotherapy, quality of life, randomized controlled trial, schizophrenia, Speech Perception, symptom, Therapy, therapy delay, therapy effect, treatment duration, treatment response, virtual reality, virtual reality exposure therapy},

pubstate = {published},

tppubtype = {article}

}

@article{yuen_acceptance_2013,

title = {Acceptance based behavior therapy for social anxiety disorder through videoconferencing},

author = {E. K. Yuen and J. D. Herbert and E. M. Forman and E. M. Goetter and A. S. Juarascio and S. Rabin and C. Goodwin and S. Bouchard},

url = {https://www.scopus.com/inward/record.uri?eid=2-s2.0-84879799248&doi=10.1016%2fj.janxdis.2013.03.002&partnerID=40&md5=a280b967176db691df32f37d15cb52a1},

doi = {10.1016/j.janxdis.2013.03.002},

issn = {18737897 (ISSN)},

year  = {2013},

date = {2013-01-01},

journal = {Journal of Anxiety Disorders},

volume = {27},

number = {4},

pages = {389–397},

abstract = {Most individuals with social anxiety disorder (SAD) do not receive any type of treatment. Reasons include logistical barriers (e.g., geographic location, travel time), fear of stigmatization, and fear of the social interactions associated with seeking treatment. Videoconferencing technology holds great promise in the widespread delivery of evidence-based treatments to those who would otherwise not receive treatment. This pilot study assessed the feasibility, acceptability, and initial efficacy of an acceptance-based behavioral intervention using Skype videoconferencing to treat adults with generalized SAD. Twenty-four participants received 12 sessions of weekly therapy and were assessed at pre-treatment, mid-treatment, post-treatment, and 3-month follow-up. Participants and therapists rated the intervention as acceptable and feasible. Analyses revealed significant pre-treatment to follow-up improvements in social anxiety, depression, disability, quality of life, and experiential avoidance, with effect sizes comparable to or larger than previously published results of studies delivering in-person CBT for SAD. Implications and future directions are discussed. © 2013 Elsevier Ltd.},

keywords = {acceptance based behavior therapy, adult, agoraphobia, alcoholism, article, avoidance behavior, Beck Depression Inventory, behavior therapy, Behavioral Assessment Test, Brief Version of the Fear of Negative Evaluation Scale, clinical article, clinical trial, comorbidity, disability, effect size, Feasibility Studies, feasibility study, female, follow up, Follow-Up Studies, generalized anxiety disorder, human, Humans, interview, Liebowitz Social Anxiety Scale, major depression, male, named inventories, panic, patient attitude, Patient Satisfaction, phobia, Phobic Disorders, Pilot Projects, pilot study, procedures, Psychiatric Status Rating Scales, psychologic test, Psychological, psychological rating scale, psychotherapist attitude, quality of life, questionnaires and rating scales, Skype, social anxiety, social phobia, Social Phobia and Anxiety Inventory, Structured Clinical Interview for DSM Disorders, telehealth, Telemedicine, Telemental health, Telepsychology, treatment outcome, videoconferencing},

pubstate = {published},

tppubtype = {article}

}

@article{michaliszyn_randomized_2010,

title = {A randomized, controlled clinical trial of in virtuo and in vivo exposure for spider phobia},

author = {D. Michaliszyn and A. Marchand and S. Bouchard and M. -O. Martel and J. Poirier-Bisson},

url = {https://www.scopus.com/inward/record.uri?eid=2-s2.0-78650262716&doi=10.1089%2fcyber.2009.0277&partnerID=40&md5=8efc6b65de8b3477ca3cd0fa8fcab93a},

doi = {10.1089/cyber.2009.0277},

issn = {21522723 (ISSN)},

year  = {2010},

date = {2010-01-01},

journal = {Cyberpsychology, Behavior, and Social Networking},

volume = {13},

number = {6},

pages = {689–695},

abstract = {The present study compared the efficacy of virtual reality (VR) in virtuo exposure and in vivo exposure in the treatment of spider phobia. Two treatment conditions were compared to a waiting-list condition. A 3-month follow-up evaluation was conducted in order to assess the durability of the treatment effects. Participants were randomly assigned to the treatment groups. A total of 16 participants received the in virtuo treatment, and 16 received the in vivo treatment. The waiting-list condition included 11 participants. Participants received eight 1.5-hour treatment sessions. Efficacy was measured with the Fear of Spiders Questionnaire, the Spider Beliefs Questionnaire (SBQ-F), and a Behavioral Avoidance Test (BAT). In addition, a clinician administered the Structured Interview for DSM-IV to assess DSM-IV's criteria for specific phobia and severity. Clinical and statistically significant improvements were found for both groups. Differences in treatment groups were found on one of five measures of fear: greater improvement on the SBQ-F beliefs subscale was associated with in vivo exposure. Copyright 2010, Mary Ann Liebert, Inc.},

keywords = {Adolescent, adult, analysis of variance, animal, Animals, article, behavior therapy, clinical trial, computer interface, Computer Simulation, controlled clinical trial, controlled study, Diagnostic and Statistical Manual of Mental Disorders, female, follow up, Follow-Up Studies, hospitalization, human, Humans, Implosive Therapy, Intention to Treat Analysis, interview, male, methodology, Middle Aged, phobia, Phobic Disorders, psychologic test, Psychological, questionnaire, Questionnaires, randomized controlled trial, Severity of Illness Index, spider, Spiders, treatment outcome, User-Computer Interface},

pubstate = {published},

tppubtype = {article}

}

@article{germain_effectiveness_2009,

title = {Effectiveness of cognitive behavioural therapy administered by videoconference for posttraumatic stress disorder},

author = {V. Germain and A. Marchand and S. Bouchard and M. -S. Drouin and S. Guay},

url = {https://www.scopus.com/inward/record.uri?eid=2-s2.0-61549135353&doi=10.1080%2f16506070802473494&partnerID=40&md5=9bfd33dc3db498732e98add612ba938a},

doi = {10.1080/16506070802473494},

issn = {16512316 (ISSN)},

year  = {2009},

date = {2009-01-01},

journal = {Cognitive Behaviour Therapy},

volume = {38},

number = {1},

pages = {42–53},

abstract = {Telehealth, or health care via videoconferencing, constitutes a clinical option that makes it possible to treat patients remotely. A growing number of studies have demonstrated that telehealth is a feasible and effective method for diagnostic interviews and psychiatric consultations. However, few studies have assessed the effectiveness of psychotherapy given by videoconference. This study examines the effectiveness of cognitive behavioural therapy (CBT) administered by videoconference for posttraumatic stress disorder (PTSD). Forty-eight participants with PTSD were recruited for the study: 16 in the videoconferencing condition and 32 in a control face-to-face condition. Each participant received CBT for 16 to 25 weeks and completed various questionnaires before and after treatment. The results show a significant decline in the frequency and severity of posttraumatic symptoms after treatment in both conditions. A clinical improvement in overall functioning was also observed. No significant difference was observed in the effectiveness of the two therapeutic conditions. The examination of effect sizes supports these results. A number of clinical implications and certain avenues for future research are discussed.},

keywords = {Adaptation, adult, aged, article, clinical article, clinical effectiveness, Cognitive behavioural therapy, cognitive therapy, controlled study, Effectiveness, female, Follow-Up Studies, health care delivery, human, Humans, intervention study, interview, male, mental function, Middle Aged, outcome assessment, Patient Acceptance of Health Care, Personality Inventory, Post-Traumatic, posttraumatic stress disorder, Psychological, Remote Consultation, Stress Disorders, telepsychotherapy, teletherapy, treatment outcome, videoconferencing},

pubstate = {published},

tppubtype = {article}

}

@article{maziade_long-term_1996,

title = {Long-term stability of diagnosis and symptom dimensions in a systematic sample of patients with onset of Schizophrenia in childhood and early adolescence. II: Positive/negative distinction and childhood predictors of adult outcome},

author = {M. Maziade and S. Bouchard and N. Gingras and L. Charron and A. Cardinal and M. -A. Roy and B. Gauthier and G. Tremblay and S. Côté and C. Fournier and P. Boutin and M. Hamel and C. Mérette and M. Martinez},

url = {https://www.scopus.com/inward/record.uri?eid=2-s2.0-0029759147&doi=10.1192%2fbjp.169.3.371&partnerID=40&md5=0b5ff36c812ac906915bb5d12769135d},

doi = {10.1192/bjp.169.3.371},

issn = {00071250},

year  = {1996},

date = {1996-01-01},

journal = {British Journal of Psychiatry},

volume = {169},

number = {3},

pages = {371–378},

abstract = {Background. The aim of this study was to verify the presence and stability across life of the positive/negative distinction in early-onset schizophrenia (EO-SZ) through a longitudinal factor analysis of the schizophrenic dimensions, and to identify the factors predicting several indices of long-term outcome for EO-SZ. Method. Forty children consecutively referred for DSM-III-R schizophrenia (SZ) in a specific catchment area comprised the sample. Results. Across a 14.8-year follow-up, longitudinal factor analysis identified two separate factors corresponding to the positive and negative symptom dimensions. We also observed that: the GAS rated over the last three years of adult illness and the severity of negative symptoms during the stabilised interepisode intervals in adulthood were the indices of adult outcome that were most easily predicted; and the best childhood predictors of adult outcome were premorbid functioning and severity of positive and negative symptoms during acute episodes. Conclusions. The presence of premorbid non-psychotic behaviour disturbances (NPBD) and premorbid developmental problems was not related to severity of outcome, in contrast to the former variables.},

note = {Publisher: Royal College of Psychiatrists},

keywords = {Adolescent, adult, article, behavior disorder, Child, Childhood, clinical article, Delusions, Depression, developmental disorder, disease course, female, Follow-Up Studies, Hallucinations, human, Humans, male, negative syndrome, onset age, Personality Development, prediction, Psychiatric Status Rating Scales, Risk Factors, schizophrenia, Schizophrenic Psychology, Schizotypal Personality Disorder},

pubstate = {published},

tppubtype = {article}

}