@article{sheehy_immersive_2025,

title = {Immersive Virtual Reality Experiences can Decrease Pain and Distress in Patients Living in Complex Care},

author = {L. Sheehy and H. Finestone and S. Bouchard and K. Dezeeuw and P. Doering and N. Dunlop and H. Sveistrup},

url = {https://www.scopus.com/inward/record.uri?eid=2-s2.0-105023893911&partnerID=40&md5=cf29113c44db0b13e00df2e34acbc141},

issn = {15548716 (ISSN)},

year  = {2025},

date = {2025-01-01},

journal = {Annual Review of CyberTherapy and Telemedicine},

volume = {23},

pages = {272–278},

abstract = {Patients living in complex care (CC) frequently experience pain. The study goals were to assess the feasibility of using virtual reality (VR), and the potential for VR to impact pain, mood, and quality of life in two groups of patients living in CC, those experiencing acute pain during wound dressing changes and those experiencing chronic pain. Participants were offered 30 minutes of immersive, passive VR experiences using a Meta Quest 2 headset, 3 times/week for 3 weeks. Pain and mood were assessed pre, during and post each VR session. Pain, mood and quality of life were assessed before and after the 3-week intervention. Feasibility was assessed after each session. Three women (average age 66.3) with wound dressing changes completed an average of 3.7 sessions (25.5 minutes/session). Two-thirds experienced meaningful declines in pain with VR. Seventeen participants (6 men, 11 women, average age 58.4) with chronic pain completed an average of 3.1 sessions (21.4 minutes/session). Pain was significantly decreased from pre to post VR and pre to during VR. Mood and quality of life did not change. Both groups had low levels of discomfort and nausea, and high levels of satisfaction and immersiveness. Most participants enjoyed the experience and appreciated the immersion. It was challenging to adapt the headset to patients in non-seated positions who could not use VR controllers. VR is a promising modality to manage pain in patients living in CC. More work needs to be done to confirm the results and implement VR in clinical settings. © 2025, Interactive Media Institute. All rights reserved.},

keywords = {adult, aged, article, chronic pain, clinical article, complex care, controlled study, discomfort, distress syndrome, female, human, immersion, male, Mood, nausea, Pain, patient care, quality of life, virtual reality, wound care},

pubstate = {published},

tppubtype = {article}

}

@article{du_sert_virtual_2018,

title = {Virtual reality therapy for refractory auditory verbal hallucinations in schizophrenia: A pilot clinical trial},

author = {O. P. Sert and S. Potvin and O. Lipp and L. Dellazizzo and M. Laurelli and R. Breton and P. Lalonde and K. Phraxayavong and K. O'Connor and J. -F. Pelletier and T. Boukhalfi and P. Renaud and A. Dumais},

url = {https://www.scopus.com/inward/record.uri?eid=2-s2.0-85042420594&doi=10.1016%2fj.schres.2018.02.031&partnerID=40&md5=fe98669ecfdfb69d05cc9ebb58fecdcc},

doi = {10.1016/j.schres.2018.02.031},

issn = {09209964},

year  = {2018},

date = {2018-01-01},

journal = {Schizophrenia Research},

volume = {197},

pages = {176–181},

publisher = {Elsevier B.V.},

abstract = {Schizophrenia is a chronic and severe mental illness that poses significant challenges. While many pharmacological and psychosocial interventions are available, many treatment-resistant schizophrenia patients continue to suffer from persistent psychotic symptoms, notably auditory verbal hallucinations (AVH), which are highly disabling. This unmet clinical need requires new innovative treatment options. Recently, a psychological therapy using computerized technology has shown large therapeutic effects on AVH severity by enabling patients to engage in a dialogue with a computerized representation of their voices. These very promising results have been extended by our team using immersive virtual reality (VR). Our study was a 7-week phase-II, randomized, partial cross-over trial. Nineteen schizophrenia patients with refractory AVH were recruited and randomly allocated to either VR-assisted therapy (VRT) or treatment-as-usual (TAU). The group allocated to TAU consisted of antipsychotic treatment and usual meetings with clinicians. The TAU group then received a delayed 7 weeks of VRT. A follow-up was ensured 3 months after the last VRT therapy session. Changes in psychiatric symptoms, before and after TAU or VRT, were assessed using a linear mixed-effects model. Our findings showed that VRT produced significant improvements in AVH severity, depressive symptoms and quality of life that lasted at the 3-month follow-up period. Consistent with previous research, our results suggest that VRT might be efficacious in reducing AVH related distress. The therapeutic effects of VRT on the distress associated with the voices were particularly prominent (d = 1.2). VRT is a highly novel and promising intervention for refractory AVH in schizophrenia. © 2018},

note = {Publisher: Elsevier B.V.},

keywords = {adult, article, auditory hallucination, auditory verbal hallucination, clinical article, clinical effectiveness, computer assisted therapy, Computer-Assisted, controlled study, Cross-Over Studies, crossover procedure, disease severity, distress syndrome, female, follow up, Follow-Up Studies, hallucination, Hallucinations, human, Humans, male, Middle Aged, neuroleptic agent, outcome assessment, Outcome Assessment (Health Care), phase 2 clinical trial, physiology, Pilot Projects, pilot study, priority journal, procedures, psychotherapy, quality of life, randomized controlled trial, schizophrenia, Speech Perception, symptom, Therapy, therapy delay, therapy effect, treatment duration, treatment response, virtual reality, virtual reality exposure therapy},

pubstate = {published},

tppubtype = {article}

}