@article{bouchard_correction_2025,

title = {Correction to: A Multisite Non-Inferiority Randomized Controlled Trial of the Efficacy of Cognitive-Behavior Therapy for Generalized Anxiety Disorder Delivered by Videoconference (Journal of Clinical Medicine, (2022), 11, 19, (5924), 10.3390/jcm11195924)},

author = {S. Bouchard and M. J. Dugas and G. Belleville and F. Langlois and P. Gosselin and G. Robillard and G. Corno and A. Marchand},

url = {https://www.scopus.com/inward/record.uri?eid=2-s2.0-85214532116&doi=10.3390%2fjcm14010226&partnerID=40&md5=16541bbb78a40461c709381c70e9ef68},

doi = {10.3390/jcm14010226},

issn = {20770383 (ISSN)},

year  = {2025},

date = {2025-01-01},

journal = {Journal of Clinical Medicine},

volume = {14},

number = {1},

abstract = {In the original publication [1], there was a mistake in Table 1 as published. The probabilities for the Chi-Square for the variable “Taking medication” of 3.38, p > 0.95. The corrected Table 1 appears below. The probabilities for the Chi-Square for the variable “Taking medication” of 3.38, p > 0.05. There was a mistake in Table 2 as published. The abbreviation for standard deviation for means reported in the column for the 6-month follow-up is D. The corrected Table 2 appears below. The abbreviation for standard deviation for means reported in the column for the 6-month follow-up is SD. There are five errors in Table 5. In the IUS Residualized change line, std Beta should be 0.56, t should be 6.44, Simple corr. should be 0.54, Partial corr. should be 0.52, Semi-Partial corr. should be 0.51. Contribution of non-specific and specific factors of CBT for GAD when delivered by videoconference or face-to-face at the second step of a hierarchical regression predicting improvements in ADIS-IV ratings. Note. ADIS-IV = Anxiety Disorders Interview Schedule-IV},

note = {Publisher: Multidisciplinary Digital Publishing Institute (MDPI)},

keywords = {erratum, female, human, Therapy},

pubstate = {published},

tppubtype = {article}

}

@article{bourbeau_role_2025,

title = {The Role of Body Image Perception on a Continuum from Dysfunctional to Healthy Eating Attitudes and Behaviors Among People Seeking Treatment},

author = {F. Bourbeau and S. Bouchard and G. Corno and J. Monthuy-Blanc},

url = {https://www.scopus.com/inward/record.uri?eid=2-s2.0-85216120423&doi=10.3390%2fjcm14020597&partnerID=40&md5=3f66a6c18a99204bfb48e9e6ad8bfe7f},

doi = {10.3390/jcm14020597},

issn = {20770383 (ISSN)},

year  = {2025},

date = {2025-01-01},

journal = {Journal of Clinical Medicine},

volume = {14},

number = {2},

abstract = {Background: Body image disturbance has been associated with various health conditions and has the potential to trigger the development of unhealthy behaviors, including dysfunctional attitudes and eating behaviors, which may evolve into eating disorders. This study explores the relationship between body image variables—such as global self-worth, physical self-worth, and physical attractiveness—and the continuum of eating attitudes and behaviors. Methods: A canonical correlation analysis was performed to assess the multivariate relationship between attitudinal and perceptual variables and the continuum of eating behaviors, with a total of 113 cases analyzed. Results: The findings indicate that intuitive eating and a positive body image (including global self-worth and physical attractiveness) are most strongly associated with the functional end of the continuum, while disordered eating behaviors and body dissatisfaction are linked to the dysfunctional end. Conclusions: These results suggest that interventions targeting the emotional and attitudinal dimensions of body dissatisfaction, whether delivered in vivo or via virtual reality (e.g., weight exposure), may facilitate a shift toward healthier, more functional eating behaviors along the continuum. © 2025 by the authors.},

note = {Publisher: Multidisciplinary Digital Publishing Institute (MDPI)},

keywords = {Adolescent, adult, aged, article, Attitude, behavior, body dissatisfaction, body dysmorphic disorder, body image, body image perception, body mass, correlation analysis, eating and attitudes and behaviors, eating disorder, Eating Disorder Examination Questionnaire, eating disorder inventory, eating habit, feeding behavior, female, healthy diet, healthy lifestyle, help seeking behavior, human, intuitive eating, major clinical study, male, Middle Aged, perception, physical attractiveness, psychological rating scale, retrospective study, Self Concept, self esteem, very elderly, virtual reality, Young Adult},

pubstate = {published},

tppubtype = {article}

}

@article{chretien_emotional_2025,

title = {Emotional Regulation in Substance-Related and Addictive Disorders Treatment: A Systematic Review},

author = {S. Chrétien and I. Giroux and I. Smith and C. Jacques and F. Ferland and S. Sévigny and S. Bouchard},

url = {https://www.scopus.com/inward/record.uri?eid=2-s2.0-85217537329&doi=10.1007%2fs10899-024-10366-8&partnerID=40&md5=6c9efe4725be6f9dd3bcd2bf347d45ec},

doi = {10.1007/s10899-024-10366-8},

issn = {10505350 (ISSN)},

year  = {2025},

date = {2025-01-01},

journal = {Journal of Gambling Studies},

volume = {41},

number = {2},

pages = {353–448},

abstract = {Emotions play an undeniable role in addictive disorders. Given the high relapse and drop-out rates still prevalent in current treatments, it is crucial to explore curative alternatives that take greater account of emotions. The primary objective of this systematic review is to gather literature related to emotion regulation in psychological addictive disorders treatments. The aim is to describe its use for individuals with behavioral (such as gambling disorder, problematic Internet gaming, and Internet addiction) or substance-related disorders. Following a screening of nearly 12,000 articles from six databases and the grey literature, 38 studies that met the selection criteria were included. The results show that 63.2% of the studies had a psychological treatment predominantly based on emotional regulation, with 81.6% (n = 31) of third-wave cognitive-behavioral interventions. The most frequently utilized intervention techniques for emotional regulation were those that facilitated an individual's awareness of their emotional state or provided psychological education to assist in identifying emotions. It would be valuable for future research to explore the most effective content for emotional regulation in treating substance-related and addictive disorders and to determine the specific client population that would benefit the most from this treatment. © The Author(s) 2025.},

note = {Publisher: Springer},

keywords = {addiction, Addictive, Addictive disorders, behavior, cognitive behavioral therapy, drug dependence, emotion regulation, Emotional Regulation, Gambling, human, Humans, internet addiction, Internet Addiction Disorder, Intervention, Non-substance-related disorders, procedures, psychology, Substance use disorders, Substance-Related Disorders, systematic review, Therapy},

pubstate = {published},

tppubtype = {article}

}

@article{guingo_efficacy_2025,

title = {Efficacy of Virtual Reality vs. Tablet Games for Pain and Anxiety in Children Undergoing Bone Pins Removal: Randomised Clinical Trial},

author = {E. Guingo and M. H. Debeurme and R. P. Santos and S. Addab and P. Rainville and S. Bouchard and K. Chougui and A. Tsimicalis and M. -L. Nault and T. Ducruet and O. Ledjiar and M. Noel and K. St-Arneault and C. Cotes-Turpin and N. Hung and P. Ouimet and S. Parent and J. Gardner and M. Bernstein and S. Le May},

url = {https://www.scopus.com/inward/record.uri?eid=2-s2.0-105004216228&doi=10.1111%2fjan.16991&partnerID=40&md5=4862f57a6a524f825f04fb1a70bb5a21},

doi = {10.1111/jan.16991},

issn = {03092402 (ISSN)},

year  = {2025},

date = {2025-01-01},

journal = {Journal of Advanced Nursing},

abstract = {Aims: To verify the efficacy of virtual reality compared to tablet games for pain and anxiety management in children undergoing percutaneous bone pin and/or suture removal procedures. Design: Randomised clinical trial using two parallel groups: (1) virtual reality or (2) tablet game. Methods: Three-center, randomised pragmatic clinical trial, using a parallel design with two groups (experimental group: immersive virtual reality; active comparator: tablet games). Children aged 6–17 requiring percutaneous pins and/or sutures were recruited between 2020 and 2022 from three outpatient orthopaedic clinics in paediatric hospitals. Pain was measured with the Numerical Rating Scale and anxiety with the Child Fear Scale before and immediately after the procedure. Results: A total of 188 participants were assigned to either the virtual reality group (96 participants) or the tablet group (92 participants). At the first assessment, there was no noticeable difference between the two groups in terms of pain or anxiety levels. However, further analysis revealed that participants aged 13 and older in the virtual reality group experienced significantly lower anxiety. Conclusion: Virtual reality was not more efficacious than games on a tablet for pain and anxiety of children undergoing removal of bone pins or sutures. However, virtual reality demonstrated a benefit in reducing anxiety for teenagers, particularly those aged 13-older. Implication for the Professional and/or Patient Care: Virtual reality games provide an immersive, non-pharmacological alternative of for anxiety management of teenagers during pins and/or sutures removal. Impact: This study showed that a virtual reality game may help reduce anxiety during pins and/or sutures removal procedures in patients aged 13 years and older. Reporting Method: We adhered to the CONSORT checklist for reporting results. Patient or Public Contribution: A patient partner reviewed the study design, methods and final manuscript. Trial Registration: NCT03680625. © 2025 The Author(s). Journal of Advanced Nursing published by John Wiley & Sons Ltd.},

note = {Publisher: John Wiley and Sons Inc},

keywords = {Anxiety, Children, Pain Management, procedural pain, virtual reality},

pubstate = {published},

tppubtype = {article}

}

@article{larochelle_intolerance_2025,

title = {Intolerance of Uncertainty and Emotion Dysregulation as Predictors of Generalized Anxiety Disorder Severity in a Clinical Population},

author = {S. Larochelle and M. J. Dugas and F. Langlois and P. Gosselin and G. Belleville and S. Bouchard},

url = {https://www.scopus.com/inward/record.uri?eid=2-s2.0-86000587548&doi=10.3390%2fjcm14051502&partnerID=40&md5=ea6c43194a821d0a0623385714231936},

doi = {10.3390/jcm14051502},

issn = {20770383 (ISSN)},

year  = {2025},

date = {2025-01-01},

journal = {Journal of Clinical Medicine},

volume = {14},

number = {5},

abstract = {Background/objectives: Several factors have been shown to play a role in the development and maintenance of generalized anxiety disorder (GAD), including intolerance of uncertainty and emotion dysregulation. Although the individual contribution of both of these factors is well documented, their combined effect has yet to be studied in a clinical population with GAD. The aim of the present study was to examine the relative contribution of intolerance of uncertainty and emotion dysregulation to the prediction of worry and GAD severity in adults with GAD. Methods: The sample consisted of 108 participants diagnosed with GAD. The participants completed measures of worry, GAD severity, depressive symptoms, intolerance of uncertainty, and emotion dysregulation. Results: Multiple regression indicated that both intolerance of uncertainty and emotion dysregulation significantly contributed to both worry and GAD severity, over and above the contribution of depressive symptoms. Of note, the model explained 36% of the variance in GAD severity scores. Conclusions: The present results provide preliminary evidence of complementarity among dominant models of GAD, and point to the potential role of integrative conceptualizations and treatment strategies for GAD. © 2025 by the authors.},

note = {Publisher: Multidisciplinary Digital Publishing Institute (MDPI)},

keywords = {adult, aged, article, Beck Depression Inventory, clinical population, comorbidity, controlled study, Depression, difficulties in emotion regulation scale, disease severity, emotion, emotion dysregulation, emotion regulation, employment status, female, generalized anxiety disorder, human, intolerance of uncertainty, Intolerance of Uncertainty Scale, major clinical study, male, patient worry, penn state worry questionnaire, prediction, predictive model, psychotherapy, Severity of Illness Index, sociodemographics, theoretical model},

pubstate = {published},

tppubtype = {article}

}

@article{orskov_virtual_2025,

title = {Virtual reality-based exposure with 360° video as part of cognitive behavioral therapy for social anxiety disorder: a three-arm randomized controlled trial},

author = {P. T. Ørskov and E. Runge and T. T. H. Sainte-Marie and M. T. Ernst and L. Clemmensen and C. H. Dalsgaard and M. B. Lichtenstein and S. Bouchard},

url = {https://www.scopus.com/inward/record.uri?eid=2-s2.0-105009844371&doi=10.3389%2ffrvir.2025.1588181&partnerID=40&md5=05dc996dceefc02747d099f6dcaed3ad},

doi = {10.3389/frvir.2025.1588181},

issn = {26734192 (ISSN)},

year  = {2025},

date = {2025-01-01},

journal = {Frontiers in Virtual Reality},

volume = {6},

abstract = {Background: Social anxiety disorder (SAD) has a high prevalence and an early onset. It often persists well into adulthood, turning into a chronic disorder. Cognitive behavioral therapy (CBT) is effective in treating SAD, but real-life exposure conducted as part of CBT is often costly and time-consuming, and imaginary exposure might lack realism and intensity. Virtual reality (VR)-based exposure using 360° video offers a promising way to deliver exposure therapy. Objective: To develop a complete psychotherapeutic treatment program including CBT with VR-based exposure using 360° videos (CBT-ExpVR) for adult patients with SAD and to test the treatment effect using the Social Interaction Anxiety Scale (SIAS) as the primary outcome. Methods: This three-arm randomized controlled trial involved 51 participants who were recruited through self-referral. The interventions took place at Center for Digital Psychiatry in Denmark. Participants were randomized via computer program to CBT-ExpVR, CBT with in vivo exposure (CBT-Exp), or an active control group offered VR relaxation (RlxVR). Afterwards, participants assigned to RlxVR were re-randomized to one of the two CBT interventions. Allocation was not blinded. Results: Intention-to-treat analysis showed that participants receiving CBT-ExpVR reported significantly fewer symptoms of social anxiety at post-treatment compared to pre-treatment, β = −14.89, 95% CI (−18.64, −11.14), p < 0.0001. At post-treatment, no difference in treatment effect was found between CBT-ExpVR and CBT-Exp, β = 3.643, 95% CI (−1.727, 9.013)},

note = {Publisher: Frontiers Media SA},

keywords = {360° video, cognitive behavioral therapy, exposure, randomized controlled trial, social anxiety disorder, virtual reality},

pubstate = {published},

tppubtype = {article}

}

@article{ernst_virtual_2024,

title = {Virtual Reality–Based Exposure With 360° Environments for Social Anxiety Disorder: Usability and Feasibility Study},

author = {M. Ernst and S. Bouchard and T. Andersen and P. T. Orskov and K. Tarp and M. B. Lichtenstein},

url = {https://www.scopus.com/inward/record.uri?eid=2-s2.0-85207452707&doi=10.2196%2f55679&partnerID=40&md5=603ff828b152a1cdbc241ab7601a43e5},

doi = {10.2196/55679},

issn = {2561326X (ISSN)},

year  = {2024},

date = {2024-01-01},

journal = {JMIR Formative Research},

volume = {8},

abstract = {Background: Social anxiety disorder (SAD) is a long-term and overwhelming fear of social situations that can affect work, school, and other daily activities. Although cognitive behavioral therapy is effective, few seek treatment, and many who do start often drop out. This may be due to the component of exposure inherent to cognitive behavioral therapy, where the patient confronts feared stimuli outside the therapist’s office, which they otherwise try to avoid. As an alternative, research has explored the effectiveness of virtual reality (VR)–based exposure therapy with promising results. However, few studies have investigated the feasibility of VR tools using mixed methodologies before assessing their efficacy. Objective: This study aims to assess the usability, feasibility, and presence of four 360° virtual environments and whether these were able to evoke anxiety in patients with SAD. Methods: A total of 10 adult participants with SAD and 10 healthy controls were recruited for 1 experimental session (age range 21-32 y; 12/20, 60% male participants). Questionnaire and interview data were collected and analyzed. A mixed methods triangulation design was applied to analyze and compare the data. Results: Participants with SAD experienced increased anxiety when exposed to VR, and environments were considered relevant and useful as an exposure tool. Participants with SAD reported significantly higher average anxiety levels (P=.01) and peak anxiety levels (P=.01) compared with controls during exposure; however, significant differences in anxiety when accounting for baseline anxiety levels were only found in 2 of 4 environments (P=.01},

note = {Publisher: JMIR Publications Inc.},

keywords = {360°, Anxiety, Exposure therapy, interactive, Mixed methods, social anxiety disorder, virtual reality},

pubstate = {published},

tppubtype = {article}

}

@article{ernst_biomarkers_2024,

title = {Biomarkers in exposure-based treatment of anxiety in virtual reality: a systematic review},

author = {M. T. Ernst and J. Hyldig Nielsen and E. Runge and S. Bouchard and L. Clemmensen},

url = {https://www.scopus.com/inward/record.uri?eid=2-s2.0-85197316386&doi=10.3389%2ffrvir.2024.1355082&partnerID=40&md5=500a06f8e6489e75933d79342b606762},

doi = {10.3389/frvir.2024.1355082},

issn = {26734192 (ISSN)},

year  = {2024},

date = {2024-01-01},

journal = {Frontiers in Virtual Reality},

volume = {5},

abstract = {Background: A large proportion of individuals with anxiety-related disorders refrain from seeking treatment. This may be because traditional exposure treatments induce anxiety. However, advances in exposure using virtual reality technology may encourage more individuals to seek treatment. Furthermore, using biomarkers with VR-based exposure may enable clinicians to assess anxiety levels objectively and collect data in a naturalistic setting. Methods: Here, we conduct a systematic review of the literature on the use of biomarkers in VR-based exposure treatment for anxiety. Twenty-seven studies were included, with a total of 1046 participants. Results: We found that heart rate was the only biomarker that tentatively could identify changes within (75% of instances) and between sessions (60% of instances). The levels of synchrony between the findings for overall biomarkers and the results from questionnaires showed inconclusive results. Regarding the levels of synchrony between the findings for particular biomarkers and the results from questionnaires, only skin conductance level was highly synchronous for differences between groups (87% of instances). Conclusion: Based on the present review, biomarkers cannot yet be used reliably to distinguish differences in self-reported symptoms of anxiety in VR-based exposure treatments. Copyright © 2024 Ernst, Hyldig Nielsen, Runge, Bouchard and Clemmensen.},

note = {Publisher: Frontiers Media SA},

keywords = {Anxiety, Biomarkers, Exposure therapy, systematic review, virtual reality},

pubstate = {published},

tppubtype = {article}

}

@article{linnaranta_views_2024,

title = {Views on a Culturally Safe Psychotherapeutic Treatment by Inuit in Quebec: Co-Design of Cognitive Behavioral Therapy Manual and Virtual Exposure Environments},

author = {O. Linnaranta and L. G. Cardona and Q. Seon and A. Tukkiapik and J. Outerbridge and S. Bouchard},

url = {https://www.scopus.com/inward/record.uri?eid=2-s2.0-85199212719&doi=10.1016%2fj.cbpra.2024.04.006&partnerID=40&md5=196f0e70c5d372d4384226d9452bc8f8},

doi = {10.1016/j.cbpra.2024.04.006},

issn = {10777229 (ISSN)},

year  = {2024},

date = {2024-01-01},

journal = {Cognitive and Behavioral Practice},

abstract = {Cognitive-behavioral psychotherapy (CBT) can be combined with virtual reality (VR) to provide culturally safe and remotely delivered emotion regulation interventions. We conducted a co-design process of a CBT treatment manual and complementary VR environments for the Inuit populations from Nunavik. Here, we describe the knowledge gained during the adaptation process on the approach to mental well-being and psychotherapy. We followed qualitative, participatory, and research co-design methods. After an initial concept of VR-CBT, an advisory group made up of 7 adults identifying as or working with Inuit participated in 4 focus group meetings. A thematic analysis of the discussions was carried out. A non-symptom-focused approach with the therapist guiding the individual in empowerment and emotion management was accepted in the advisory group, replacing a symptom-focus. Several CBT in- and between-session techniques were seen critically or rejected, and time for working on a certain theme was increased. Some elements in the proposed landscape were rejected as unsafe, other elements added as culture-specific to increase safety. Future work should confirm broader acceptance and utility. Culturally specific factors play an essential role in acceptance of concepts and approaches used in psychotherapy. Accordingly, they can have an impact on acceptance and attendance in therapy. © 2024},

note = {Publisher: Elsevier Inc.},

keywords = {cognitive behavioral therapy, cultural adaptation, cultural safety, emotion regulation, Inuit, participatory co-design, virtual reality},

pubstate = {published},

tppubtype = {article}

}

@article{sheehy_development_2024,

title = {Development and Initial Testing of an Artificial Intelligence-Based Virtual Reality Companion for People Living with Dementia in Long-Term Care},

author = {L. Sheehy and S. Bouchard and A. Kakkar and R. El Hakim and J. Lhoest and A. Frank},

url = {https://www.scopus.com/inward/record.uri?eid=2-s2.0-85205071099&doi=10.3390%2fjcm13185574&partnerID=40&md5=844732ff858a0d5feb0a95a54093ad4d},

doi = {10.3390/jcm13185574},

issn = {20770383 (ISSN)},

year  = {2024},

date = {2024-01-01},

journal = {Journal of Clinical Medicine},

volume = {13},

number = {18},

abstract = {Background/Objectives: Feelings of loneliness are common in people living with dementia (PLWD) in long-term care (LTC). The goals of this study were to describe the development of a novel virtual companion for PLWD living in LTC and assess its feasibility and acceptability. Methods: The computer-generated virtual companion, presented using a head-mounted virtual reality display, was developed in two stages. In Stage 1, the virtual companion asked questions designed to encourage conversation and reminiscence. In Stage 2, more powerful artificial intelligence tools allowed the virtual companion to engage users in nuanced discussions on any topic. PLWD in LTC tested the application at each stage to assess feasibility and acceptability. Results: Ten PLWD living in LTC participated in Stage 1 (4 men and 6 women; average 82 years old) and Stage 2 (2 men and 8 women; average 87 years old). Session lengths ranged from 0:00 to 5:30 min in Stage 1 and 0:00 to 53:50 min in Stage 2. Speech recognition issues and a limited repertoire of questions limited acceptance in Stage 1. Enhanced conversational ability in Stage 2 led to intimate and meaningful conversations with many participants. Many users found the head-mounted display heavy. There were no complaints of simulator sickness. The virtual companion was best suited to PLWD who could engage in reciprocal conversation. After Stage 2, response latency was identified as an opportunity for improvement in future versions. Conclusions: Virtual reality and artificial intelligence can be used to create a virtual companion that is acceptable and enjoyable to some PLWD living in LTC. Ongoing innovations in hardware and software will allow future iterations to provide more natural conversational interaction and an enhanced social experience. © 2024 by the authors.},

note = {Publisher: Multidisciplinary Digital Publishing Institute (MDPI)},

keywords = {aged, article, Artificial intelligence, cognitive decline, cognitive impairment, compassion, conversation, dementia, Elderly, female, human, large language models, long term care, long-term care, major clinical study, male, program acceptability, program feasibility, reaction time, reminiscence, speech discrimination, very elderly, virtual reality},

pubstate = {published},

tppubtype = {article}

}